Results 91 to 100 of about 61,568 (292)
Med Research, EarlyView.ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin +8 more
wiley +1 more source
Immune Characterization of a Vietnamese Cohort With Idiopathic Inflammatory Myopathies
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Idiopathic inflammatory myopathies (IIMs) are classified into five subtypes that are associated with distinct groups of myositis‐specific antibodies (MSAs). Variations in the prevalence, genetic predisposition and clinical manifestations exist in patients with IIM from different ethnic backgrounds.
Yue‐Bei Luo +8 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Although the need for malignancy screening in idiopathic inflammatory myopathies (IIM) is generally accepted, data to guide the choice and timing of investigations are limited. Our aim was to characterize the gaps and uncertainties amongst Canadian neurologists and rheumatologists with respect to malignancy screening in IIM ...
Maria Jekielek +3 more
wiley +1 more source
Responsive Materials, EarlyView.This review comprehensively discusses intelligent peptide‐based nanomaterials from the design, mechanisms, properties, and applications, taking stimuli responsiveness as a starting point. Abstract Bacterial infections pose a major threat to human health as well as livestock production. Traditional antibiotics face significant limitations in the complex
Chenlong Zhou +8 more
wiley +1 more source
Ruxolitinib in adult dermatomyositis with anti-TIF1γ antibody: a case report and literature review
Frontiers in ImmunologyRuxolitinib is a selective JAK1/2 inhibitor, and its application in treating adult-onset dermatomyositis(DM) has rarely been described. Here, we report a case of an adult-onset DM patient with anti-TIF1γ antibody, who also suffered from essential ...
Xu Jing, Wang Min, Liu Xia, Li Shanshan
doaj +1 more source
Veterinary Record Case Reports, EarlyView.Abstract Renal potassium wasting syndromes, such as Gitelman's syndrome (GS), are well documented in humans but rarely reported in veterinary medicine. This case describes a 6‐month‐old domestic medium‐hair cat presenting with chronic hypokalaemia, polyuria and polydipsia. Diagnostic evaluation revealed hypokalaemia, metabolic alkalosis, hypochloraemia
Kyle L. Granger Jr. +2 more
wiley +1 more source
Annals of the Rheumatic Diseases, 2020 As shown by Kostine et al ,1 and recently underlined by Ceccarelli et al ,2 rheumatic inflammatory disorders induced by anticancer therapy are becoming a major concern for rheumatologists at the era of immune checkpoint inhibitors (ICIs).
Thủy Nguyễn +12 more
semanticscholar +1 more source
Systemic lupus erythematosus-myositis overlap syndrome with lupus nephritis
Journal of Family Medicine and Primary Care, 2020 Systemic lupus erythematosus-myositis overlap syndrome is rare with prognostic implications. Reports suggest that systemic lupus erythematosus-myositis overlap syndrome with lupus nephritis has a variable clinical outcome.
Biswajit Dey +3 more
doaj +1 more source
New insights into the treatment of myositis
Therapeutic Advances in Musculoskeletal Disease, 2020 The myositis syndromes include polymyositis, dermatomyositis (DM), necrotizing myopathy, inclusion body myositis (IBM), antisynthetase syndrome and overlap syndromes with myositis.
S. Glaubitz, Rachel Zeng, Jens Schmidt
semanticscholar +1 more source