Results 51 to 60 of about 50,140 (235)
Idiopathic Inflammatory Myopathies; Association with Overlap Myositis and Syndromes: Classification, Clinical Characteristics, and Associated Autoantibodies [PDF]
Idiopathic inflammatory myopathies (IIM) are traditionally identified as a group of disorders that target skeletal muscle due to autoimmune dysfunction.
Pari Basharat
core
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko +4 more
wiley +1 more source
Tongue myositis in dermatomyositis with anti-PM-Scl 75 antibody: two case reports
Background Dermatomyositis (DM) is a heterogeneous disease characterized by skin rash and muscle weakness. Although tongue disorders have been documented in idiopathic inflammatory myopathies (IIM), biopsy-confirmed tongue myositis remains exceedingly ...
Chao Sun +4 more
doaj +1 more source
Focal myositis is a pseudotumor of soft tissue that typically occurs in the deep soft tissue of the extremities, and is a relatively rare lesion. There is a wide clinical spectrum, with approximately one-third of patients with focal myositis subsequently
Sweet, Donald E +2 more
core +1 more source
In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype. [PDF]
The aim of this study was to investigate HLA class II associations in polymyositis (PM) and dermatomyositis (DM), and to determine how these associations influence clinical and serological differences.
Hector Chinoy +33 more
core +1 more source
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil +7 more
wiley +1 more source
Objectives We assessed the positive predictive value (PPV) of 17 myositis antibodies for having a diagnosis of myositis and other myositis-spectrum conditions (interstitial lung disease (ILD), connective tissue diseases (CTD), malignancy) and evaluated ...
Anne M Kerola +4 more
doaj +1 more source
ZusammenfassungEntzündliche Muskelerkrankungen stellen eine wichtige Gruppe der seltenen neuromuskulären Erkrankungen dar. Die Diagnose der Myositiden hat einen besonderen Stellenwert, da sie im Gegensatz zu vielen anderen hereditären neuromuskulären ...
W. Müller-Felber +7 more
core +1 more source
Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali +11 more
wiley +1 more source
Osmolytes as mediators of the muscle tissue’s responses to inflammation : emerging regulators of myositis with therapeutic potential [PDF]
Chronic inflammation of skeletal muscle tissues termed myositis is associated with inherited muscular dystrophy and with acquired inflammatory myopathy.
Boel De Paepe, De Paepe, Boel
core

