Results 51 to 60 of about 37,717 (247)

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

Angewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee, Jung Min Kim, Joseph Blecha, Robert R. Flavell, Michael A. Ohliger, Joanne Engel, Youngho Seo, David M. Wilson   +7 more
wiley   +2 more sources

Baricitinib could improve the prognosis of anti-MDA5 antibody positive dermatomyositis associated interstitial lung disease

Arthritis Research & Therapy
Background and objective Currently, there are only a few effective treatments for anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5) positive dermatomyositis (DM)-associated interstitial lung disease (ILD).
Shuai Zhu, Shanshan Li, Lipu Shi, Tianshu Chu, Zhenguo Huang, Xin Lu, Guochun Wang, Yongpeng Ge   +7 more
doaj   +1 more source

Mind over matter? A cross-sectional study exploring the influence of depression versus physical disability on patient-reported wellbeing in inclusion body myositis

Brain Disorders
This cross-sectional study aimed to explore the relationships between physical disability, depression, and wellbeing in people with inclusion body myositis, a rare and progressively disabling muscle disease.
G. Nunn, G. Simkovics, K. Hird, K. Beer, I. Cooper, M. Needham   +5 more
doaj   +1 more source

Necrotizing autoimmune myositis following coronavirus disease 2019 infection: a case report

Journal of Medical Case Reports, 2022
Background Severe acute respiratory syndrome coronavirus 2 may be associated with late-onset necrotizing myositis, mimicking autoimmune inflammatory myositis; however, the exact underlying pathogenesis of severe acute respiratory syndrome coronavirus 2 ...
Maryam Loghman, Ehsan Rahmanian, Majid Alikhani, Hiva Saffar, Sara Beikmohamadi Hezaveh, Mohammad Nekooeian, Reza Shahriarirad, Seyedeh Tahereh Faezi   +7 more
doaj   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

A new hope with CAR T-cell therapy for refractory idiopathic inflammatory myopathies: a systematic review

Journal of Translational Medicine
Background Treatment options for refractory idiopathic inflammatory myopathies (IIMs) remain limited, and sustained remission is frequently not achieved with conventional immunosuppression or biologic agents.
Xueyan Shan, Fengtao Pang, Guochun Wang, Yongpeng Ge, Xin Lu   +4 more
doaj   +1 more source

Idiopathic inflammatory myopathy: From muscle biopsy to serology

Indian Journal of Rheumatology, 2020
Idiopathic inflammatory myopathies (IIMs) are heterogeneous group of muscle disorders characterized by variable degree of muscle weakness and muscle inflammation. Various classification systems have been proposed for myositis.
Ritu Verma, Vimal Kumar Paliwal
doaj   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Tongue myositis in dermatomyositis with anti-PM-Scl 75 antibody: two case reports

BMC Musculoskeletal Disorders
Background Dermatomyositis (DM) is a heterogeneous disease characterized by skin rash and muscle weakness. Although tongue disorders have been documented in idiopathic inflammatory myopathies (IIM), biopsy-confirmed tongue myositis remains exceedingly ...
Chao Sun, Xiaolan Tian, Shanshan Li, Guochun Wang, Xin Lu   +4 more
doaj   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source