Results 41 to 50 of about 50,140 (235)

Immune-Mediated Necrotizing Myopathy Associated With Myelodysplastic Syndrome

Annals of Internal Medicine: Clinical Cases, 2023
Autoimmune diseases can often be diagnosed in patients with myelodysplastic syndrome (MDS). Here, we review the emerging literature linking MDS and rare presentations of autoimmunity, including myositis.
Katherine M. Sheu, Benedict K. Tiong, Meika A. Fang, Ari Weinreb   +3 more
doaj   +1 more source

Diplopia Due to Orbital Myositis: Diagnosis with Magnetic Resonance Imaging

, 2019
Orbital myositis is a non-specific inflammatory disease primarily affecting the extraocular muscles. It is most commonly seen in young adults and women and is often unilateral.
İnci Güngör, Muzaffer Elmali, Aslı Tanrıvermiş Sayıt   +2 more
core   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

Arthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

Baricitinib could improve the prognosis of anti-MDA5 antibody positive dermatomyositis associated interstitial lung disease

Arthritis Research & Therapy
Background and objective Currently, there are only a few effective treatments for anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5) positive dermatomyositis (DM)-associated interstitial lung disease (ILD).
Shuai Zhu, Shanshan Li, Lipu Shi, Tianshu Chu, Zhenguo Huang, Xin Lu, Guochun Wang, Yongpeng Ge   +7 more
doaj   +1 more source

Mind over matter? A cross-sectional study exploring the influence of depression versus physical disability on patient-reported wellbeing in inclusion body myositis

Brain Disorders
This cross-sectional study aimed to explore the relationships between physical disability, depression, and wellbeing in people with inclusion body myositis, a rare and progressively disabling muscle disease.
G. Nunn, G. Simkovics, K. Hird, K. Beer, I. Cooper, M. Needham   +5 more
doaj   +1 more source

Necrotizing autoimmune myositis following coronavirus disease 2019 infection: a case report

Journal of Medical Case Reports, 2022
Background Severe acute respiratory syndrome coronavirus 2 may be associated with late-onset necrotizing myositis, mimicking autoimmune inflammatory myositis; however, the exact underlying pathogenesis of severe acute respiratory syndrome coronavirus 2 ...
Maryam Loghman, Ehsan Rahmanian, Majid Alikhani, Hiva Saffar, Sara Beikmohamadi Hezaveh, Mohammad Nekooeian, Reza Shahriarirad, Seyedeh Tahereh Faezi   +7 more
doaj   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

A new hope with CAR T-cell therapy for refractory idiopathic inflammatory myopathies: a systematic review

Journal of Translational Medicine
Background Treatment options for refractory idiopathic inflammatory myopathies (IIMs) remain limited, and sustained remission is frequently not achieved with conventional immunosuppression or biologic agents.
Xueyan Shan, Fengtao Pang, Guochun Wang, Yongpeng Ge, Xin Lu   +4 more
doaj   +1 more source

Tendon Transfers to Improve Grip and Pinch in Patients with Sporadic Inclusion Body Myositis

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. Sporadic inclusion body myositis (sIBM) is a rare and slowly progressive skeletal muscle disease that can cause hand dysfunction, which is a major source of disability.
Catherine Hua, BA, Salman Bhai, MD, Jonathan Cheng, MD, Jose Hinojosa, MS, Lynn Wilson, BS, Manuel Lubinus, MBA, PhD, Abhiram R. Bhashyam, MD, PhD   +6 more
doaj   +1 more source