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Anxiogenic activity of Myristica fragrans seeds
Pharmacology Biochemistry and Behavior, 2002In the present study, the n-hexane extract of Myristica fragrans (MF) seeds, acetone-insoluble part of the n-hexane extract (AIMF) and trimyristin (TM) were assessed for their anxiogenic activity. The MF (10 and 30 mg/kg), AIMF (30, 100, and 300 mg/kg), and TM (10, 30, and 100 mg/kg) administered intraperitoneally exhibited anxiogenic activity in ...
G S, Sonavane +3 more
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Biological effects of Myristica fragrans (nutmeg) extract
Phytotherapy Research, 1999The chloroform extract of nutmeg has been evaluated for antiinflammatory, analgesic and antithrombotic activities in rodents. The extract inhibited the carrageenan-induced rat paw oedema, produced a reduction in writhings induced by acetic acid in mice and offered protection against thrombosis induced by ADP/adrenaline mixture in mice.
O A, Olajide +5 more
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Antibacterial Principles from Myristica fragrans Seeds
Journal of Medicinal Food, 2006Nutmeg (Myristica fragrans) is used in food preparations for its aromatic flavor. The present investigation was undertaken to evaluate the antibacterial activity of constituents of M. fragrans seeds. Seeds of M. fragrans were powdered and extracted with chloroform to obtain trimyristin, which on saponification yielded myristic acid.
Balasubramanian, Narasimhan +1 more
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Further antibacterial compounds from Myristica fragrans
Investigational Medicinal Chemistry and Pharmacology, 2018Background: Myristica fragrans Houtt is a medicinal food plant of the family Myristicaceae. Previous phytochemical investigation of its seed kernel known as nutmeg led to the isolation of antibacterial flavonoid, 3’,4’,7-trihydroxyflavone. The present study aimed at identifying further antibacterials of the crude methanol extract from nutmeg.
Joachim K. Dzotam +7 more
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Procoagulant Substance and Mechanism of Myristica fragrans
Journal of Medicinal Food, 2016The effect and mechanisms of Myristica fragrans on blood clotting were evaluated by evaluating blood coagulation time and the fibrinolytic system. The compounds 2 and 5 were isolated from the herbal extract and their activities were assessed for the first time.
Yong, Zhang +3 more
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Diarylpropanoids from nutmeg and mace (Myristica fragrans Houtt.)
Journal of the Chemical Society, Perkin Transactions 1, 1974Some diarylpropanoid (bis-C6–C3) type compounds have been isolated during the course of a search for the psychoactive components present in the seed (nutmeg) and aril (mace) of the fruit of Myristica fragrans Houtt. The presence of two different structural types, analogous to the β-O-4 ether and 2,3-dihydrobenzofuran types of dilignols, has been ...
J E, Forrest, R A, Heacock, T P, Forrest
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[New neolignan from seed of Myristica fragrans].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009To study the chemical constituents in the nutmeg (seed of Myristica fragrans).The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by IR, NMR and MS evidences.Fifteen compounds were obtained and identified as myristicin (1), methyleugenol (2), safrole (3), 2, 3-dihydro-7-methoxy-2(3, 4 ...
Xiu-Wei, Yang, Xin, Huang, Mamat, Ahmat
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Myristica fragrans Houtt. (Myristicaceae)
In this present review work, nutmeg and mace from Myristica fragrans Houtt. were elaborated associated with their risks in use. Nutmeg, as a spice and medicinal preparation, is known and documented to be used as a carminative, expectorant, and analgesic and also used in infants.Ayşe Esra KARADAĞ, Fatih DEMİRCİ
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Improvement of Mouse Memory by Myristica fragrans Seeds
Journal of Medicinal Food, 2004Memory is one of the most complex functions of the brain and involves multiple neural pathways and neurotransmitter systems. The present study was undertaken to investigate the effect of Myristica fragrans (MF) seeds on learning and memory in mice.
Milind, Parle +2 more
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The structure of macelignan from Myristica fragrans
Phytochemistry, 1987Abstract A new lignan, macelignan, isolated from the arils of Myristica fragrans , is shown to have the structure (2 R ,3 S )-1-(3,4-methylenedioxyphenyl)-2,3-dimethyl-4-(4-hydroxy-3-methoxyphenyl)-butane by spectral analysis, chemical conversion and X-ray crystallographic analysis.
Won Sick Woo +3 more
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