Results 101 to 110 of about 593,619 (307)
“Irrevocable Words,” or Why Maria Kirilovna “Deceived” Dubrovsky
The features of the plot behaviour of Maria Kirilovna Troekurova, the main character of the novel “Dubrovsky,” are discusses. The relevance of the study is due to the lack of works explaining one of the main mysteries of Pushkin’s text - the discrepancy ...
S. A. Larin
doaj +1 more source
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. The variable copy number (CN) of C4 genes and retroviral human endogenous retrovirus K (HERV‐K) element influence its function.
Javier Martínez‐López +156 more
wiley +1 more source
Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith +23 more
wiley +1 more source
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang +9 more
wiley +1 more source
Association of Clonal Hematopoiesis with Incident, Late‐Onset, Seropositive Rheumatoid Arthritis
Objectives Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA)
Kun Zhao +8 more
wiley +1 more source
Mystery Shopping: In-depth measurement of customer satisfaction [PDF]
This paper will discuss the phenomenon Mystery Shopping in the fieldof customer satisfaction measurement techniques. By using theliterature about Mystery Shopping definitions and restrictions of thisinstrument will be presented.
Hesselink, M., Wiele, A. van der
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Abstract According to Nietzsche, “In every real [adult], a child is hidden that wants to play.” In everyday life, playfulness and competition can make routine or dull tasks more engaging and can offer educators opportunities to engage a learner in a more entertaining or interactive manner.
Judi Laprade
wiley +1 more source
THE COGNITIV MODEL BLAGA – POPPER [PDF]
In the proposed research there is a comparative analysis of two conceptions – of the English thinker Karl R. Popper (1902-1994) and of the Romanian thinker Lucian Blaga (1895 – 1961), thinkers who launched the idea of a new model of knowledge and that ...
NEGRU NICOLAE
doaj
This paper examines why developed countries are monogamous while rich men throughout history have tended to practice polygyny (multiple wives). Wealth inequality naturally produces multiple wives for rich men in a standard model of the marriage market ...
Gould, Eric D., Moav, Omer, Simhon, Avi
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Unvollendetes: the Oxford Plato lexicon [PDF]
In one obvious sense this paper is a misfit within a book that otherwise charts so much achievement. The unfinished project that it describes occupied the attention of two Scottish professors and, in its later reincarnation, a distinguished German ...
Whitaker, G.
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