Results 81 to 90 of about 202,994 (344)

A Crystalline and Thermally Stable Selenocysteine Selenenic Acid

open access: yesAngewandte Chemie, EarlyView.
The long‐sought catalytic intermediate of selenoproteins, selenocysteine selenenic acid (Sec–SeOH), is isolated for the first time at ambient temperature. A bioinspired selenopeptide sequence encapsulated within a protective molecular cradle and an oxidant‐free route from selenenyl iodide (Sec–SeI) enable the isolation of Sec–SeOH. Contrary to the long‐
Ryosuke Masuda, Satoru Kuwano, Kei Goto
wiley   +2 more sources

The aesthetics of Harold Pinter's dramatic art [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2011
The British playwright Harold Pinter (1930-2008) is undoubtedly one of the greatest and most extraordinary modern playwrights, with the writing career which spanned over fifty years.
Šoškić Radoje V.
doaj  

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng   +16 more
wiley   +1 more source

El territorio de la espiritualidad naturalizada

open access: yesScientia et Fides, 2015
(The territory of Naturalized Spirituality)The change of territory from religion to spirituality in our secular societies has given rise to the so-called naturalized spirituality within the naturalist tradition. We critically discuss O.W. Flanagan and S.
Camino Cañón Loyes
doaj   +1 more source

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling

open access: yesAdvanced Science, EarlyView.
Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang   +11 more
wiley   +1 more source

The Mysteries of Rural Architecture [PDF]

open access: yesمسکن و محیط روستا, 2010
The rural architecture is all about house it starts with a house and yet it ends with a house. The rural house is quite simple and calm, but in the meanwhile it enjoys some complexity in the sense of wisdom.

doaj  

Une étude en noir

open access: yesTracés, 2011
Why did crime fiction first establish itself on the basis of a distinction, or even opposition, between the character of the detective and that of the police officer ?
Luc Boltanski
doaj   +1 more source

Methusalem’s mystery [PDF]

open access: yesProtoplasma, 2014
Life is limited—at least for multicellular animals. The separation between differentiating somatic cells and the germ line also delineates the separation between mortality and eternal life. We are so tantalised by induced pluricellular stem cells, because they promise the option to cross this line.
openaire   +3 more sources

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

open access: yesAdvanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao   +13 more
wiley   +1 more source

Meaning of Mystery as Process of Deification

open access: yesReligions
“Mystery” is a term with divergent meanings in the religious and secular worlds. This term bears history in the philosophical and theological worlds.
George Thomas Kuzhippallil
doaj   +1 more source

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