Results 61 to 70 of about 128,808 (294)
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu +14 more
wiley +1 more source
“You Are Engulfed with Misfortune because You Are a Sinner”
Job was written as a dialectic to refute the theology of reward and punishment of the Deuteronomistic theology. Using rhetorical approach, this article analyses Job 4:1–9, a passage where Eliphaz responds to Job’s lament by advising him to accept ...
Damian O. Odo, Dirk Human
doaj +1 more source
The aesthetics of Harold Pinter's dramatic art [PDF]
The British playwright Harold Pinter (1930-2008) is undoubtedly one of the greatest and most extraordinary modern playwrights, with the writing career which spanned over fifty years.
Šoškić Radoje V.
doaj
The IgLec gene family generates both protein‐coding antiviral effectors and non‐coding transcripts. Upon viral infection, non‐coding transcripts are preferentially targeted by viral miR‐N48, thereby buffering protein‐coding isoforms from repression. Depletion of these decoy transcripts compromises antiviral defense, revealing a non‐coding RNA‐mediated ...
Ying Huang +5 more
wiley +1 more source
El territorio de la espiritualidad naturalizada
(The territory of Naturalized Spirituality)The change of territory from religion to spirituality in our secular societies has given rise to the so-called naturalized spirituality within the naturalist tradition. We critically discuss O.W. Flanagan and S.
Camino Cañón Loyes
doaj +1 more source
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng +17 more
wiley +1 more source
The Mysteries of Rural Architecture [PDF]
The rural architecture is all about house it starts with a house and yet it ends with a house. The rural house is quite simple and calm, but in the meanwhile it enjoys some complexity in the sense of wisdom.
doaj
Why did crime fiction first establish itself on the basis of a distinction, or even opposition, between the character of the detective and that of the police officer ?
Luc Boltanski
doaj +1 more source
Chemoresistance is often linked to elevated DNA repair. MPP8 is found to promote breast cancer chemoresistance as a novel NHEJ accessory factor independent of its epigenetic functions. Through multiple protein interactions, MPP8 facilitates association of DNAPK and ligase complexes to promote DNA repair progression.
Rupa Kumari, Jia Fang
wiley +1 more source
Double Reduction of Ph3B to a Dianionic Borane With a Powerful SrI Intermediate
Although dianionic boranes follow the octet rule and are isoelectronic to carbanions or amines, the high electron density combined with the electropositive nature of the B center make them highly unstable species. In this study, we present synthesis and full characterization of a complex in which Ph3B2− is sandwiched between two Sr2+ ions and describe ...
Michael Morasch +4 more
wiley +2 more sources

