Results 41 to 50 of about 202,994 (344)
Interferon pathway in SLE: one key to unlocking the mystery of the disease
Lupus Science and Medicine, 2019 SLE is characterised by an activation of the interferon (IFN) system, which leads to an increased expression of IFN-regulated genes. The reasons behind the IFN signature in SLE are (1) the existence of endogenous IFN inducers, (2) activation of several ...
L. Rönnblom, D. Leonard
semanticscholar +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Rules of How Reality Works Through the Prism of Post-Postmodern Prose
Czytanie Literatury, 2020 The reviewer analyses the monograph Problematic-Thematic Units and Philosophical-Esthetical Parameters of the British Post-Postmodern Novel (Kyiv, 2020) written by Dmytro Drozdovskyi, a Ukrainian scholar from Taras Shevchenko Institute of Literature of
Mykoła Zymomria
doaj +1 more source
The Antioxidant Role of Non-mitochondrial CoQ10: Mystery Solved!
Cell Metabolism, 2020 Although confirmed as the primary lipophilic antioxidant molecule endogenously produced by cells, the non-mitochondrial pool of CoQ10's functional role is still well debated. Recently, both Bersuker et al. (2019) and Doll et al.
M. Santoro
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Recherches Germaniques, 2023 This article deals with Eugen Gomringer’s ideograms and their translations. It points out that there is no loss of meaning in the different versions in German, French, English, and Spanish.
Walter Schilling
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Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
NATURE, HISTORY, AND GOD: TOWARD AN INTEGRATED CONCEPTUALIZATION
Zygon, 1992 . In this paper I attempt to bring the ancient symbol God into a meaningful and illuminating conceptual relationship with modern understandings of the development of the cosmos, the evolution of life, and the movements of human history.
doaj +2 more sources
Simon Weil and Contradiction [PDF]
Journal of Philosophical InvestigationsPhilosophers' confrontation with contradiction is so fundamental and important that it has been a trend in the history of philosophy. Simone Weil is one of the philosophers who has a different view on the problem of contradiction.
Mostafa Mousavi-Azam
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Journal of Hospitality and Tourism Insights, 2020 PurposeQuality in foodservices has become essential, and new methodological ways of determining service quality enable a better representation of service processes and help to increase revisits.
B. Bichler, B. Pikkemaat, M. Peters
semanticscholar +1 more source