Results 51 to 60 of about 128,808 (294)
Advanced Science, EarlyView.This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song +9 more
wiley +1 more source
Advanced Science, EarlyView.Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou +11 more
wiley +1 more source
Mystery Cults in Visual Representation in Graeco-Roman Antiquity /
Mystery Cults in Visual Representation in Graeco-Roman Antiquity aims to fill a gap in the study of mystery cults in Graeco-Roman Antiquity by focusing on images for investigating their ritual praxis.
Belayche, Nicole,editor. +1 more
core +1 more source
Advanced Science, EarlyView.The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu +4 more
wiley +1 more source
Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
Solving a 3.2-Million-Year-Old Mystery: How Lucy Died [PDF]
, 2017 Since its discovery in 1974, Lucy, a 3.2-million-year-old specimen of Australopithecus afarensis - or “southern ape of Afar” has provided invaluable information about human evolution. However, Lucy’s death has always remained a mystery.
Environmental Science Institute +1 more
core +1 more source
Unveiling the Artificial Neural Network Mystery with Special Reference to Applications in Civil Engineering [PDF]
Computational Engineering and Physical ModelingOver the past few decades, Artificial Neural Networks (ANN) have carved a niche within the Civil Engineering applications and has been a supplementary to the traditional mathematical models.
Shreenivas Londhe +5 more
doaj +1 more source
Advanced Science, EarlyView.Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu +12 more
wiley +1 more source
Mystery Shopping: In-depth measurement of customer satisfaction [PDF]
This paper will discuss the phenomenon Mystery Shopping in the fieldof customer satisfaction measurement techniques. By using theliterature about Mystery Shopping definitions and restrictions of thisinstrument will be presented.
Hesselink, M., Wiele, A. van der
core
Senseless Pain in the Phenomenology of Religious Experience
Open Theology, 2020 There are three models of pain in the phenomenology of religious experience. The first model suggests that pain is instrumental to attaining the desired religious experience.
Salim Emil
doaj +1 more source