Results 11 to 20 of about 29,137 (174)

Case report: Atypical spindle cell/pleomorphic lipomatous tumor masquerading as a myxoid liposarcoma or intramuscular myxoma

Frontiers in Oncology, 2022
Atypical spindle cell/pleomorphic lipomatous tumors (ASPLTs) were recently categorized as benign lipomatous tumors. However, accurate and complete preoperative diagnosis of ASPLTs may be difficult.
J. Ichikawa, T. Kawasaki, H. Imada, Satoshi Kanno, N. Taniguchi, Tomoyuki Ashizawa, H. Haro   +6 more
semanticscholar   +1 more source

FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma

Frontiers in Oncology, 2022
Myxoid liposarcoma is one of the most common sarcoma entities characterized by FET fusion oncogenes. Despite a generally favorable prognosis of myxoid liposarcoma, chemotherapy resistance remains a clinical problem.
S. Dolatabadi, Emma Jonasson, Lisa Andersson, Manuel Luna Santamaría, M. Lindén, Tobias Österlund, P. Åman, A. Ståhlberg   +7 more
semanticscholar   +1 more source

Primary High-Grade Myxoid Liposarcoma of the Extremities: Prognostic Factors and Metastatic Pattern

Cancers, 2022
Simple Summary Around 12–25% of patients with high-grade myxoid liposarcoma (MLS) develop local relapses and 30–60% develop pulmonary or extrapulmonary metastases over a 10-year follow-up period.
G. Tuzzato, Roberta Laranga, Federico Ostetto, Elisa Bubbico, G. Vara, G. Bianchi   +5 more
semanticscholar   +1 more source

Nuclear expression of DDIT3 distinguishes high-grade myxoid liposarcoma from other round cell sarcomas

Modern Pathology, 2021
Myxoid liposarcoma (MLPS) is a malignant adipocytic neoplasm with predilection for the extremities. MLPS is genetically defined by a t(12;16) translocation leading to FUS–DDIT3 (95%) or more rarely t(12;22) leading to EWSR1–DDIT3.
E. Baranov, M. Black, C. Fletcher, G. Charville, J. Hornick   +4 more
semanticscholar   +1 more source

Intermuscular extremity myxoid liposarcoma can be managed by marginal resection following neoadjuvant radiotherapy.

European Journal of Surgical Oncology, 2022
BACKGROUND Compared with other soft tissue sarcomas, myxoid liposarcoma (MLS) occurs in younger patients, has a propensity for intermuscular locations and is highly radiosensitive.
Jonathan R. Perera, Meshal AlFaraidy, Izuchukwu K Ibe, Ahmed A. Aoude, I. Acem, M. A. van de Sande, Mireille Dessureault, R. Turcotte, S. Mottard, G. Basile, M. Isler, Hugo Saint-Yves, N. Eastley, J. Stevenson, M. Houdek, P. Chung, A. Griffin, P. Ferguson, J. Wunder, K. Tsoi   +19 more
semanticscholar   +1 more source

High prevalence of TERT aberrations in myxoid liposarcoma: TERT reactivation may play a crucial role in tumorigenesis

Cancer Science, 2021
Myxoid liposarcoma (MLPS) is genetically characterized by FUS‐DDIT3 or EWSR1‐DDIT3 gene fusion and the high frequency of hotspot mutations (C228T or C250T) in the promoter region of telomerase reverse transcriptase (TERT) that encodes the TERT protein ...
Junko Kunieda, Kyoko Yamashita, Yuki Togashi, Satoko Baba, S. Sakata, K. Inamura, K. Ae, S. Matsumoto, R. Machinami, M. Kitagawa, K. Takeuchi   +10 more
semanticscholar   +1 more source

Crosstalk between Macrophages and Myxoid Liposarcoma Cells Increases Spreading and Invasiveness of Tumor Cells

Cancers, 2021
Simple Summary Myxoid liposarcoma (MLPS) is the second most common subtype of liposarcoma, occurs predominantly in the extremities, and tends either to recur locally and metastasize to unusual soft tissue locations.
M. Minopoli, S. Sarno, L. Cannella, S. Tafuto, G. Scognamiglio, M. Gallo, F. Fazioli, Rosa Azzaro, G. Apice, B. De Angelis, E. Tamborini, C. Garofalo, Y. Pignochino, L. Mercatali, T. Ibrahim, R. Falcioni, B. Valenti, R. Maestro, K. Scotlandi, A. De Chiara, M. Carriero   +20 more
semanticscholar   +1 more source

Well-Differentiated Liposarcoma of the Hypopharynx Exhibiting Myxoid Liposarcoma-like Morphology with MDM2 and DDIT3 Co-Amplification

Head and Neck Pathology, 2021
Well-differentiated liposarcoma (WDL) is one of the most common soft tissue sarcomas in adults. It has a predilection for middle-aged males and arises in deep-seated locations such as retroperitoneum, mediastinum, and spermatic cord.
Khaled A. Murshed, Hayan Abo Samra, Adham Ammar   +2 more
semanticscholar   +1 more source

Myxoid liposarcoma of bladder

International Journal of Surgery Case Reports, 2021
Abstract Introduction Myxoid liposarcoma of the bladder is a rare mesenchymal tumor which is difficult to diagnose and carries a poor prognosis. The primary treatment is complete surgical resection which is usually followed by adjuvant chemotherapy.
Chudal, Sampanna, Poudyal, Sujeet, Chapagain, Suman, Luitel, Bhoj Raj, Chalise, Pawan Raj, Sharma, Uttam Kumar   +5 more
openaire   +2 more sources

Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial.

JAMA Oncology, 2020
Importance Currently, preoperative radiotherapy for all soft-tissue sarcomas is identical at a 50-Gy dose level, which can be associated with morbidity, particularly wound complications.
J. Lansu, J. Bovée, P. Braam, H. V. Van Boven, U. Flucke, J. Bonenkamp, A. Miah, S. Zaidi, K. Thway, Ø. Bruland, E. Baldini, N. Jebsen, A. Scholten, P. V. D. van den Ende, A. Krol, J. F. Ubbels, J. A. van der Hage, E. van Werkhoven, H. Klomp, W. V. D. van der Graaf, F. van Coevorden, Y. Schrage, W. V. van Houdt, R. Haas   +23 more
semanticscholar   +1 more source