Results 21 to 30 of about 29,137 (174)

Myxoid pleomorphic liposarcoma is distinguished from other liposarcomas by widespread loss of heterozygosity and significantly worse overall survival: a genomic and clinicopathologic study

Modern Pathology, 2022
Myxoid pleomorphic liposarcoma (MPLPS) is a recently described and extremely rare subtype of liposarcoma with a predilection for the mediastinum. However, the genomic features of MPLPS remain poorly understood.
J. Dermawan, Sinchun Hwang, L. Wexler, W. Tap, S. Singer, Chad M. Vanderbilt, C. Antonescu   +6 more
semanticscholar   +1 more source

Letetresgene Autoleucel in Advanced/Metastatic Myxoid/Round Cell Liposarcoma

Journal of Clinical Oncology
PURPOSE The cancer/testis antigen New York esophageal squamous cell carcinoma 1 (NY-ESO-1) is a promising target in myxoid/round cell liposarcoma (MRCLS).
S. D’Angelo, M. Druta, B. V. Van Tine, D. Liebner, S. Schuetze, W. Tap, J. Preston, S. Goodison, Jimson W D'souza, G. S. Kapoor, Sunil Suchindran, Stefan Zajic, Aishwarya Bhaskar, Heather Kaczynski, Jaegil Kim, E. Klohe, Ellie Corigliano, I. Eleftheriadou, M. Nathenson, N. Somaiah   +19 more
semanticscholar   +1 more source

SPEARHEAD-1: a single-arm phase 2 trial of afamitresgene autoleucel (afami-cel) in advanced synovial sarcoma and myxoid/round cell liposarcoma

The Lancet
Summary Background Afamitresgene autoleucel (afami-cel) showed acceptable safety and promising efficacy in a phase 1 trial (NCT03132922). This study evaluated afami-cel’s efficacy in human leukocyte antigen (HLA)-A*02–positive patients with melanoma ...
S. D’Angelo, D. Araujo, A. Razak, M. Agulnik, S. Attia, J. Blay, I. García, J. Charlson, Edwin Choy, G. Demetri, M. Druta, Edouard Forcade, Kristen N. Ganjoo, J. Glod, V. Keedy, A. Le Cesne, D. Liebner, V. Moreno, Seth M. Pollack, S.M. Schuetze, Gary K. Schwartz, S. Strauss, W. Tap, F. Thistlethwaite, C.M. Valverde Morales, M. Wagner, B. Wilky, Cheryl McAlpine, L. Hudson, J. Navenot, Tianjiao Wang, S. Rafail, Ruoxi Wang, Amy Sun, Lilliam Fernandes, E. Van Winkle, E. Elefant, C. Lunt, E. Norry, Dennis Williams, S. Biswas, B. V. Van Tine   +41 more
semanticscholar   +1 more source

DDIT3 immunohistochemistry is a useful tool for the diagnosis of myxoid liposarcoma

American Journal of Surgical Pathology, 2020
Myxoid liposarcoma is a malignant adipogenic neoplasm characterized by prominent arborizing capillaries, occasional lipoblasts, and primitive-appearing spindle cells in a myxoid background.
Jason V. Scapa, J. Cloutier, S. Raghavan, Grace Peters-Schulze, S. Varma, G. Charville   +5 more
semanticscholar   +1 more source

[Myxoid liposarcoma].

Revue medicale de Liege, 2009
Soft-tissue sarcoma is a rare pathology. Due to restricted symptomatology, the diagnosis is often late. Any soft tissues swelling requires at first an ultrasound exam and a radiography, though MRI remains the most appropriate investigation. Treatment will be selected according to the tumor type and its histological grading, these parameters being ...
F, Douchamps, W, Kurth, J M, Crielaard
openaire   +3 more sources

Myxoid pleomorphic liposarcoma.

Histology and histopathology
Myxoid pleomorphic liposarcoma (MPL) is an extremely rare adipocytic tumor, recently recognized as a distinct entity in the 5th edition of the World Health Organization (WHO) Classification of Soft Tissue and Bone Tumors. Predominantly found in the mediastinum of young women, MPLs exhibit a combination of histological features characteristic of myxoid ...
Fadaei, Sharareh, Cordier, Fleur, Ferdinande, Liesbeth, Van Dorpe, Jo, Creytens, David   +4 more
openaire   +3 more sources

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching, Anderson S. M. Leung, Raymond C. H. Yau, Albert Y. L. Lam, Tony W. H. Shek, Maximus C. F. Yeung   +5 more
wiley   +1 more source

Dedifferentiation in endometrial cancer is associated with HLA‐I silencing that may be restored by IFN‐γ

The Journal of Pathology, EarlyView.
Abstract Dedifferentiated endometrial carcinoma occurs when a prognostically favorable low‐grade endometrial carcinoma transforms into a highly aggressive undifferentiated carcinoma following genomic inactivation of core SWItch/Sucrose Non‐Fermentable (SWI/SNF) complex protein(s).
Antonio De Leo, Madison Wickenberg, Marco Grillini, Camelia Alexandra Coadǎ, Pooja Praveen Kumar, Annie Tong, James Key, Hannah Kim, Felix Kommoss, Mark Carey, Yangxin Fu, Claudio Ceccarelli, Giovanni Tallini, Paul LaPointe, Martin Köbel, Cheng‐Han Lee   +15 more
wiley   +1 more source

Retroperitoneal perirenal myxoid liposarcoma [PDF]

Journal of Surgical Case Reports, 2015
Liposarcomas are neoplasms of mesodermic origin, are derived from adipose tissue and represent
Crisan, Nicolae, Ivan, Cristina S., Bungardean, Catalina, Cebotaru, Cristina, Coman, Ioan   +4 more
openaire   +2 more sources

Exploring Neutrophil Extracellular Traps in Canine Soft Tissue Sarcomas: A Preliminary Study With Translational Insights

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Neutrophil Extracellular Traps (NETs) in Canine Soft Tissue Sarcomas This study investigated the presence of neutrophil extracellular traps (NETs) in canine soft tissue sarcomas using dual immunohistochemistry for citrullinated histone‐3 and myeloperoxidase.
Burak Yildirim, Volkan Ipek
wiley   +1 more source