Results 161 to 170 of about 4,101 (195)
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Nature, 1955
IT is well known that myxomatosis has caused a high mortality among wild rabbit populations in most parts of England and Wales, and in those parts of Scotland and Ireland to which the disease has spread. Where it has been possible to make accurate observations, a mortality-rate of about 99 per cent was found. A similar death-rate was usual in Australia
J R, HUDSON, H V, THOMPSON, W, MANSI
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IT is well known that myxomatosis has caused a high mortality among wild rabbit populations in most parts of England and Wales, and in those parts of Scotland and Ireland to which the disease has spread. Where it has been possible to make accurate observations, a mortality-rate of about 99 per cent was found. A similar death-rate was usual in Australia
J R, HUDSON, H V, THOMPSON, W, MANSI
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Immune Responses to Myxoma Virus
Viral Immunology, 2002Myxoma virus causes the systemic disease myxomatosis in the European rabbit (Oryctolagus cuniculus). Originating in the South American rabbit Sylvilagus brasiliensis, where it causes a relatively localized fibroma, myxoma virus is a classic example of a virus that has jumped species to produce an exotic disease and then coevolved with its new host ...
Peter, Kerr, Grant, McFadden
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Electron Microscopy of Myxoma Virus
Nature, 1963Ruska and Kausche1 and Farrant and Fenner2 demonstrated a close similarity, both in size and superficial morphology, between myxoma and vaccinia viruses. This, together with the demonstration of similarity in the pathogenesis of myxomatosis and other pox virus diseases, was considered by the latter authors to justify the inclusion of myxoma virus ...
P J, CHAPPLE, J C, WESTWOOD
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Immunomodulation by viruses: the myxoma virus story
Immunological Reviews, 1999Summary: Myxoma virus is a poxvirus pathogen of rabbits that has evolved to replicate successfully in the presence of an active immune response by an infected host. To accomplish this, the virus has developed a variety of strategies to avoid detection by or obstruct specific aspects of the antiviral response whose consolidated action is antagonistic ...
P, Nash +11 more
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Ultrastructural study of myxoma virus morphogenesis
Archives of Virology, 2006Poxviruses are among the largest and most complex viruses known. Vaccinia virus, the prototype of the family Poxviridae, has been studied much more than myxoma virus. The aim of this work was to have a better knowledge about myxoma virus morphogenesis.
Duteyrat, Jl +2 more
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The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics [PDF]
Microbes and Infection, 2010 Myxoma virus (MYXV) is a poxvirus with a strict rabbit-specific host-tropism for pathogenesis. The immunoregulatory factors encoded by MYXV can suppress some functions of immune effectors from other species. We review their mechanisms of action, implications in therapeutics and the potential to improve MYXV as an oncolytic agent in humans.
Jia Liu, Grant Mcfadden
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Virology, 2000 The coevolution of myxoma virus and the wild European rabbit in Australia and the development of resistance to myxomatosis in wild rabbits have been well described. However, the mechanism of resistance to myxomatosis in wild rabbits is not understood. To
Sonja M Best, Peter J Kerr
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Rapid purification of myxoma virus DNA
Journal of Virological Methods, 2009A rapid and efficient procedure for the purification of myxoma virus DNA from infected cell cultures is described. The traditional method used for recovery of myxoma virus DNA involves multiple freeze-thawing cycles to disrupt cells and release virions followed by ultracentrifugation to concentrate virions for DNA extraction.
Kevin P, Dalton +3 more
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Some aspects of the morphogenesis of myxoma virus in vivo
Archiv f�r die gesamte Virusforschung, 1972The replication of myxoma virus was examined using thin sections of rabbit skin. The virus is assembled in the cytoplasm as crescent shaped structures which eventually form complete immature particles. These are roughly spherical, contain granular material and are limited by a unit membrane bearing spicules on its outer surface.
D A, Purcell, J K, Clarke
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Occurrence of Attenuated Strains of Myxoma Virus in Europe
Nature, 1955SEVERAL slightly attenuated strains of myxoma virus have been recovered from the field in Australia1; indeed, it is now rather uncommon to recover strains having the same high virulence as the material used for initiating the epizootics, and for the subsequent inoculation campaigns.
F, FENNER, I D, MARSHALL
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