Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]
, 2019 Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F +22 more
core +3 more sources
NeuroImage: Clinical, 2017 Multiple sclerosis (MS) is a pathologically complex CNS disease: inflammation, demyelination, and neuroaxonal degeneration occur concurrently and may depend on one another.
Emily Turner Wood +5 more
doaj +1 more source
Magnetic resonance spectroscopy in Parkinson’s disease
Бюллетень сибирской медицины, 2020 Introduction. Modern neuroimaging methods allow to evaluate in vivo biochemical processes in the brain. Such methods include magnetic resonance spectroscopy (MRS) and positron emission tomography (PET). While PET is the “golden standard” in assessing the
Y. G. Khomenko +6 more
doaj +1 more source
Striatal N-Acetylaspartate Synthetase Shati/Nat8l Regulates Depression-Like Behaviors via mGluR3-Mediated Serotonergic Suppression in Mice [PDF]
, 2017 Background: Several clinical studies have suggested that N-acetylaspartate and N-acetylaspartylglutamate levels in the human brain are associated with various psychiatric disorders, including major depressive disorder. We have previously identified Shati/
Aoki +54 more
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Frontal Metabolite Concentration Deficits in Opiate Dependence Relate to Substance Use, Cognition, and Self-Regulation. [PDF]
, 2016 ObjectiveProton magnetic resonance spectroscopy (1H MRS) in opiate dependence showed abnormalities in neuronal viability and glutamate concentration in the anterior cingulate cortex (ACC).
Abé, Christoph +5 more
core +1 more source
The Involvement of the GH/IGF-I Axis in Cognitive Functions of Adult Patients and Healthy Subjects [PDF]
, 2012 This thesis describes three automated precolumn derivatization procedures for the analysis of carboxylic group-containing compounds. After derivatization with a suitable label, the derivatives are separated on reversed-phashed HPLC and detected by ...
Deijen, J.B., Drent, M.L., Driel, M.I.
core +7 more sources
Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol. [PDF]
, 2018 Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery.
Durazzo, Timothy C +3 more
core +2 more sources
Modeling neurocognitive and neurobiological recovery in addiction [PDF]
, 2019 This book focuses on "what to know" and "how to apply" information, prioritizing novel principles and delineating cutting-edge assessment, phenotyping and treatment ...
Abé +179 more
core +1 more source
Chronic Stress, 2018 Background The anterior cingulate gyrus is involved in the extinction of conditioned fear responses and is implicated in the pathophysiology of posttraumatic stress disorder.
Ana Carolina Coelho Milani +7 more
doaj +1 more source
Magnetic Resonance Spectroscopy Role in Assessment of Pediatric Supratentorial Brain Lesions [PDF]
International Journal of Medical Arts, 2022 Background: Magnetic resonance spectroscopy [MRS] is of value for pediatric neurologist, as it confers relevant information from the clinical point of view. It is worth for brain tumors, infections and disorders of the white matter.
Ahmad Abdallah Elsayed Elgamal +2 more
doaj +1 more source