OGT Regulates β1,4-GlcNAc-branched N-glycan Biosynthesis Via the OGT/SLC35A3/GnT-IV Axis [PDF]
, 2022 東北医科薬科大学博士（薬科学）令和3年度doctoral ...
ソン, ワンリ, 宋, 万里
core
Advanced Science, Volume 12, Issue 38, October 13, 2025.This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang +11 more
wiley +1 more source
Altered Cell Surface N-Glycosylation of Resting and Activated T Cells in Systemic Lupus Erythematosus [PDF]
, 2019 Altered cell surface glycosylation in congenital and acquired diseases has been shown to affect cell differentiation and cellular responses to external signals.
Bocskai, Márta +5 more
core +2 more sources
Glycomic Analysis of Biomedically Important O-glycoconjugates
, 2011 It has been established that all cells carry an array of glycans attached to proteins and lipids that are crucial in the interaction between cells and the surrounding matrix. Proteins are mainly glycosylated on asparagines (N-glycosylation) and serine or
Ismail, Mohd Nazri, Ismail, Mohd Nazri
core +1 more source
The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition [PDF]
, 2011 Six genes involved in the heparan sulfate and heparin metabolism pathway, DSEL (dermatan sulfate epimerase-like), EXTL1 (exostoses (multiple)-like 1), HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), HS6ST3 (heparan sulfate 6-O-sulfotransferase 3 ...
Jiang, Zhihua +4 more
core +1 more source
Predominant Expression of Hybrid N-Glycans Has Distinct Cellular Roles Relative to Complex and Oligomannose N-Glycans [PDF]
, 2016 Glycosylation modulates growth, maintenance, and stress signaling processes. Consequently, altered N-glycosylation is associated with reduced fitness and disease.
Austin Whitman +12 more
core +2 more sources
Functional analysis of N-acetylglucosaminyltransferase-I: a novel regulator of epithelial-mesenchymal transition [PDF]
, 2019 東北医科薬科大学博士（薬科学）平成30年度doctoral ...
チャン, ゴウェイ, 張, 国偉
core
.ALPHA.1,4-N-acetylglucosaminyltransferase and gastroenterology.
SEIBUTSU BUTSURI KAGAKU, 2002 Mucous glycoproteins secreted from the gastroduodenal mucosa and pancreatic duct showing gastric metaplasia characteristically contain GlcNAcα1→4Galβ→R structures in terminal ends of O-glycans, and this unique carbohydrate is frequently expressed in gastric cancer cells.
Jun Nakayama +4 more
openaire +2 more sources
Golgi proteomics : Identification of a novel cartilage-specific Golgi protein GoPro49 [PDF]
, 2009 The Golgi complex is a central organelle of the secretory pathway, responsible for a range of post-translational modifications, as well as for membrane traffic to the plasma membrane and to the endosomal-lysosomal pathway. In addition, this organelle has
Takatalo, Maarit
core
Engineering glycan-binding proteins for the detection, analysis and treatment of cancer cells
, 2010 Aberrant glycosylation in cancer cells can often lead to an increase in the exposure of unusual glycan structures. The presence of these structures can be exploited by engineering glycan-binding proteins as novel tools for the characterisation of ...
Powlesland, Alex Stephen +1 more
core +1 more source