An Unprecedented Medium-Chain Diunsaturated N-acylhomoserine Lactone from Marine Roseobacter Group Bacteria [PDF]
Marine Drugs, 2018 N-acylhomoserine lactones (AHLs), bacterial signaling compounds involved in quorum-sensing, are a structurally diverse group of compounds. We describe here the identification, synthesis, occurrence and biological activity of a new AHL, N-((2E,5Z)-2,5 ...
Lisa Ziesche +7 more
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Selection of the N-acylhomoserine lactone-degrading bacterium Alteromonas stellipolaris PQQ-42 and of its potential for biocontrol in aquaculture [PDF]
Frontiers in Microbiology, 2016 The production of virulence factors by many pathogenic microorganisms depends on the intercellular communication system called quorum sensing (QS), which involves the production and release of signal molecules known as autoinducers.
Marta eTorres +5 more
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Interference of Quorum Sensing by Delftia sp. VM4 Depends on the Activity of a Novel N-Acylhomoserine Lactone-Acylase. [PDF]
PLoS ONE, 2015 Turf soil bacterial isolate Delftia sp. VM4 can degrade exogenous N-acyl homoserine lactone (AHL), hence it effectively attenuates the virulence of bacterial soft rot pathogen Pectobacterium carotovorum subsp.
Vimal B Maisuria, Anuradha S Nerurkar
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Genetic and Biochemical Diversity for N-Acylhomoserine Lactone Biosynthesis in the Plant Pathogen Pectobacterium carotovorum subsp. Carotovorum [PDF]
Microbes and Environments, 2019 The plant pathogen Pectobacterium carotovorum subsp. carotovorum (Pcc) regulates the expression of virulence factors by N-acylhomoserine lactone (AHL)-mediated quorum sensing. The LuxI family protein, ExpI, catalyzes AHL biosynthesis in Pcc.
Xiaonan Xie, Tomohiro Morohoshi
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The interaction of N-acylhomoserine lactone quorum sensing signaling molecules with biological membranes: implications for inter-kingdom signaling. [PDF]
PLoS ONE, 2010 The long chain N-acylhomoserine lactone (AHL) quorum sensing signal molecules released by Pseudomonas aeruginosa have long been known to elicit immunomodulatory effects through a process termed inter-kingdom signaling.
Benjamin Michael Davis +3 more
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The Pseudomonas aeruginosa N-acylhomoserine lactone quorum sensing molecules target IQGAP1 and modulate epithelial cell migration. [PDF]
PLoS Pathogens, 2012 Quorum sensing (QS) signaling allows bacteria to control gene expression once a critical population density is achieved. The Gram-negative human pathogen Pseudomonas aeruginosa uses N-acylhomoserine lactones (AHL) as QS signals, which coordinate the ...
Thommie Karlsson +4 more
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A Bacterial Isolate Capable of Quenching Both Diffusible Signal Factor- and <i>N</i>-Acylhomoserine Lactone-Family Quorum Sensing Signals Shows Much Enhanced Biocontrol Potencies. [PDF]
J Agric Food Chem, 2022 N-Acylhomoserine lactone (AHL) and diffusible signal factor (DSF) molecules are two families of widely conserved quorum sensing (QS) signals. Quorum quenching (QQ) via enzymatic inactivation of QS signals is a promising strategy of biocontrol.
Wang H +8 more
europepmc +2 more sources
Characterization of
BMC Microbiology, 2011 Background Cell-to-cell communication (quorum sensing (QS)) co-ordinates bacterial behaviour at a population level. Consequently the behaviour of a natural multi-species community is likely to depend at least in part on co-existing QS and quorum ...
Chhabra Siri +7 more
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Short-Chain N-Acylhomoserine Lactone Quorum-Sensing Molecules Promote Periodontal Pathogens in In Vitro Oral Biofilms. [PDF]
Appl Environ Microbiol, 2020 Dental plaque is omnipresent in healthy oral cavities and part of our commensal microbial colonization. At the same time, dental plaque is the cause of the most common human diseases, caries and gum disease. Dental plaque consists of billions of microbes
Muras A +7 more
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Short Synthesis of Structurally Diverse N-Acylhomoserine Lactone Analogs and Discovery of Novel Quorum Quenchers Against Gram-Negative Pathogens. [PDF]
Int J Mol SciQuorum quenchers are emerging as an alternative to conventional antimicrobials, since they hinder the development of virulence or resistance mechanisms but without killing the microorganisms, thus, reducing the risk of antimicrobial resistance.
Porras M, Hernández D, Boto A.
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