Scalable multi-enzyme platforms for the in vitro glycoengineering of therapeutic proteins & synthesis of human milk oligosaccharides [PDF]
, 2022 Sugars in their free form or conjugated to biomolecules like proteins, lipids, and small molecules have significant functional roles in different biological processes.
Mahour, R.
core +2 more sources
Legionella pneumophila in Municipal Shower Systems in Stavanger, Norway; A Longitudinal Surveillance Study Using Whole Genome Sequencing in Risk Management [PDF]
, 2022 Following an incidence of Legionnaires disease (LD) in 2007, where a municipal shower system was the likely source of infection, Stavanger municipality initiated a surveillance program for Legionella as part of establishing internal risk evaluation and ...
Austerheim, Elin +5 more
core +1 more source
Label-free mass spectrometry proteome quantification of human embryonic kidney cells following 24 hours of sialic acid overproduction [PDF]
, 2013 Peer ...
Joenväärä, Sakari +3 more
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Assessment of viral community functional potential from viral metagenomes may be hampered by contamination with cellular sequences. [PDF]
, 2013 International audienceAlthough the importance of viruses in natural ecosystems is widely acknowledged, the functional potential of viral communities is yet to be determined.
Debroas, Didier +4 more
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Pulmonary Circulation, Volume 5, Issue 4, Page 667-680, December 2015., 2015 Increased proliferation and resistance to apoptosis of pulmonary arterial vascular smooth muscle cells (PAVSMCs), coupled with metabolic reprogramming, are key components of pulmonary vascular remodeling, a major and currently irreversible pathophysiological feature of pulmonary arterial hypertension (PAH).
Tatiana V. Kudryashova +6 more
wiley +1 more source
Spatial structuring of a Legionella pneumophila population within the water system of a large occupational building. [PDF]
, 2018 The diversity of Legionella pneumophila populations within single water systems is not well understood, particularly in those unassociated with cases of Legionnaires' disease. Here, we performed genomic analysis of 235 L.
Chalker, Victoria J +6 more
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Implementation of molecular techniques in the diagnosis of legionnaires’ disease and in the investigation of legionella outbreaks [PDF]
, 2016 Background. Legionnaires’ Disease (LD) is a mild to severe, potentially lethal, respiratory syndrome caused by members of the Legionella genus, in particular L. pneumophila serogroup (sg) 1 alone causes about 95% of culture confirmed cases. The infection
Mentasti, M., Mentasti, M.
core
Absence of miRNA-146a Differentially Alters Microglia Function and Proteome [PDF]
, 2020 Background: MiR-146a is an important regulator of innate inflammatory responses and is also implicated in cell death and survival. Methods: By sorting CNS resident cells, microglia were the main cellular source of miR-146a.
Aboo, C +14 more
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Interactions of the Skin Pathogen Haemophilus ducreyi With the Human Host [PDF]
, 2021 The obligate human pathogen Haemophilus ducreyi causes both cutaneous ulcers in children and sexually transmitted genital ulcers (chancroid) in adults. Pathogenesis is dependent on avoiding phagocytosis and exploiting the suppurative granuloma-like niche,
Brothwell, Julie A. +3 more
core +1 more source
PHGDH Heterogeneity Potentiates Cancer Cell Dissemination and Metastasis [PDF]
, 2022 Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs1. Genetic, transcriptional and translational heterogeneity contributes to this dynamic process2,3.
Alkan, H Furkan +50 more
core +3 more sources