Sequence- and structure-based approaches to deciphering enzyme evolution in the Haloalkonoate Dehalogenase superfamily [PDF]
, 2016 Understanding how changes in functional requirements of the cell select for changes in protein sequence and structure is a fundamental challenge in molecular evolution.
Pandya, Chetanya
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Investigating Host Microbiota Relationships Through Functional Metagenomics [PDF]
, 2019 The human Intestinal mucus is formed by glycoproteins, the O- and N-linked glycans which constitute a crucial source of carbon for commensal gut bacteria, especially when deprived of dietary glycans of plant origin.
Bejar, Nada +13 more
core +3 more sources
Protein distribution during human erythroblast enucleation in vitro [PDF]
, 2013 Enucleation is the step in erythroid terminal differentiation when the nucleus is expelled from developing erythroblasts creating reticulocytes and free nuclei surrounded by plasma membrane.
Bell, Amanda J. +8 more
core +2 more sources
Unravelling the evolution of the Allatostatin-Type A, KISS and Galanin Peptide-Receptor gene families in Bilaterians: insights from Anopheles Mosquitoes [PDF]
, 2015 Allatostatin type A receptors (AST-ARs) are a group of G-protein coupled receptors activated by members of the FGL-amide (AST-A) peptide family that inhibit food intake and development in arthropods.
A della Torre +122 more
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Quantum Chemical Modeling, Synthesis, Spectroscopic (FT-IR, Excited States, UV/VIS) Studies, FMO, QTAIM, ELF, LOL, NBO, NLO and QSAR Analyses of Nelarabine [PDF]
, 2023 In this study, we report the results of experiments and density functional theory (DFT), time-dependent DFT, and quantitative structure-activity relationship (QSAR) analyses of (2R,3S,4S,5R)-2- (2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl ...
Kaviani, S. +6 more
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The Involvement of the Cas9 Gene in Virulence of Campylobacter jejuni [PDF]
, 2018 Campylobacter jejuni is considered as the leading cause of gastroenteritis all over the world. This bacterium has the CRISPR–cas9 system, which is used as a gene editing technique in different organisms.
Guyue Cheng +11 more
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Purification and characterization of GlcNAc-6-P 2-epimerase from Escherichia coli K92 [PDF]
[EN]N-Acetylmannosamine (ManNAc) is the first committed intermediate in sialic acid metabolism. Thus, the mechanisms that control intracellular ManNAc levels are important regulators of sialic acid production.
Ezquerro Sáenz, Carlos +6 more
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Supplementary Data for “Sequence and annotation of the 314-kb MT325 and the 321-kb FR483 viruses that infect \u3ci\u3eChlorella\u3c/i\u3e Pbi”: Appendix B: Gene Names M001L through M807R [PDF]
, 2007 Appendix B: Gene Names M001L through M807R Document, in spreadsheet format, shows Gene Name, Genome Position, A.A. length, Peptid e Mw, pI, CDD Hit Number, COGs, COG Definition, Bit Score, E-value, % Identity, % Positive, Query from-to, Hit from-to ...
Feldblyum, Tamara +5 more
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Exploring novel chemical and enzymatic labelling approaches in metabolic oligosaccharide engineering of mammalian cells [PDF]
, 2021 Glycoproteins have many important roles in cell signalling and diseases including cancer, neurodegeneration, and pathogenic infections. Metabolic oligosaccharide engineering has previously been used to incorporate unnatural sugar derivatives into ...
Hayes, Jenny Alex
core
Fluorescence-based pH-shift assay with wide application scope for high-throughput determination of enzymatic activity in enzyme mining and engineering [PDF]
A number of enzymes important for biocatalyst development or as drug targets are associated with a pH shift during their catalytic reaction, owing to the concommitant release or uptake of protons.
Fessner, Wolf-Dieter +2 more
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