Results 71 to 80 of about 779,528 (296)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Orbital Stability and Secular Dynamics of the Proxima Centauri Planetary System

The Astrophysical Journal
The two innermost planets of the Proxima Centauri system are separated by just 0.02 au, inducing strong gravitational interactions between them. We assess this interaction by leveraging fast orbital stability indicators and find that orbital stability is
Joseph R. Livesey, Rory Barnes, Russell Deitrick   +2 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

A Freefall-based Switching Criterion for P3T Hybrid N-body Methods in Collisional Stellar Systems

The Astrophysical Journal
The P ^3 T scheme is a hybrid method for simulating gravitational N -body systems. It combines a fast particle-tree (PT) algorithm for long-range forces with a high-accuracy particle–particle (PP; direct N -body) solver for short-range interactions ...
Long Wang, David M. Hernandez, Zepeng Zheng, Wanhao Huang   +3 more
doaj   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Evolution of Star Clusters within Galaxies Using Self-consistent Hybrid Hydro/N-body Simulations

The Astrophysical Journal
We introduce a GPU-accelerated hybrid hydro/ N -body code ( Enzo-N ) designed to address the challenges of concurrently simulating star clusters and their parent galaxies.
Yongseok Jo, Seoyoung Kim, Ji-hoon Kim, Greg L. Bryan   +3 more
doaj   +1 more source

On Encounter Rates in Star Clusters

The Astrophysical Journal, 2023
Close encounters between stars in star-forming regions are important as they can perturb or destroy protoplanetary disks, young planetary systems, and multiple-star systems.
Krisada Rawiraswattana, Simon P. Goodwin
doaj   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Astrophysical N-Body Simulations: Algorithms and Challenges [PDF]

, 2001
The subjects and key questions faced by computational astrophysics using N-body simulations are discussed in the fields of globular star cluster dynamics, galactic nuclei and cosmological structure formation. After a comparison of the relevance of different N-body algorithms a new concept for a more flexible customized special purpose computer based on
openaire   +2 more sources

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

Arthritis Care &Research, EarlyView.
Objective Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla, Timothy G. Brandon, Dmitry Khrichenko, Rui Xiao, Nancy A. Chauvin, Asef Khwaja, Pamela F. Weiss   +6 more
wiley   +1 more source