Results 131 to 140 of about 13,066,219 (329)

Mass spectrometric profiling reveals association of -glycan patterns with epithelial ovarian cancer progression

Tumor Biology, 2017
Aberrant changes of N -glycan modifications on proteins have been linked to various diseases including different cancers, suggesting possible avenue for exploring their etiologies based on N -glycomic analysis.
Huanhuan Chen, Zaian Deng, Chuncui Huang, Hongmei Wu, Xia Zhao, Yan Li   +5 more
doaj   +1 more source

Glycan-dependent and -independent Association of Vesicular Stomatitis Virus G Protein with Calnexin*

Journal of Biological Chemistry, 1996
Calnexin (CNX) is a membrane-bound molecular chaperone that associates with newly synthesized proteins in the endoplasmic reticulum. Although several studies have indicated that it interacts exclusively with glycoproteins that carry monoglucosylated N ...
Kurt S. Cannon, D. Hebert, A. Helenius
semanticscholar   +1 more source

Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells. [PDF]

, 2016
Alpha1,2-fucosyltransferases, FUT1 and FUT2, which transfer fucoses onto the terminal galactose of N-acetyl-lactosamine via α1,2-linkage have been shown to be highly expressed in various types of cancers.
Cho, Huan-Chieh, Ho, Ming-Yi, Hung, Jung-Tung, Tan, Keng-Poo, Yu, Alice Lin-Tsing, Yu, John   +5 more
core  

Machine Learning‐Enhanced Analysis of Exosomal Surface Sialic Acid Using Surface‐Enhanced Raman Spectroscopy for Ovarian Cancer Diagnosis and Therapeutic Monitoring

Advanced Science, EarlyView.
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong, Jiaqi Wang, Sijun Huang, Xiaxia Man, Yi Guo, Shuping Xu, Songling Zhang   +6 more
wiley   +1 more source

Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei [PDF]

, 2014
Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans.
Acosta-Serrano, Angela Mehlert, Atrih, Bangs, Bangs, Bendiak, Chang, Cross, Cross, Cross, Di Wu, Doering, Ferguson, Ferguson, Giraudo, Grab, Güther, Harpaz, Ho, Hwa, Ioffe, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Izquierdo, Joao A. Rodrigues, Jones, Kornfeld, Leal, Lombard, M.Lucia S. Güther, Manthri, Manuela Damerow, Mazhari-Tabrizi, Mehlert, Mehlert, Mehlert, Mehlert, Mehlert, Metzler, Michael A.J. Ferguson, Milne, Nagamune, Narimatsu, Nolan, Paschinger, Paulson, Pays, Rovis, Schachter, Sonnhammer, Tabas, Tazeh, Urbaniak, Vella, Visser, Wiggins, Wirtz, Wiśniewski, Zamze   +60 more
core   +3 more sources

Microenvironment‐Guided Evolution of ssDNA‐SWCNT Probes for Selective Recognition of Aggressive Prostate Cancer Phenotypes

Advanced Science, EarlyView.
Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee, Seok‐Hyeon Lee, Yunseo Jung, Jeongho Lee, Min‐Seo Choi, SaeOck Oh, Sungjee Kim, Byoung Soo Kim, Sanghwa Jeong   +8 more
wiley   +1 more source

Simultaneous Glycan-Peptide Characterization Using Hydrophilic Interaction Chromatography and Parallel Fragmentation by CID, Higher Energy Collisional Dissociation, and Electron Transfer Dissociation MS Applied to the N-Linked Glycoproteome of Campylobacter jejuni*

Molecular & Cellular Proteomics, 2010
Campylobacter jejuni is a gastrointestinal pathogen that is able to modify membrane and periplasmic proteins by the N-linked addition of a 7-residue glycan at the strict attachment motif (D/E)XNX(S/T).
Nichollas E. Scott, B. Parker, Angela M. Connolly, Jana Paulech, A. Edwards, B. Crossett, L. Falconer, D. Kolarich, S. Djordjevic, P. Højrup, N. Packer, M. Larsen, S. Cordwell   +12 more
semanticscholar   +1 more source

Diagnostic accuracy of urinary prostate protein glycosylation profiling in prostatitis diagnosis [PDF]

, 2015
Introduction: Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in
Decaestecker, Karel, Delanghe, Joris, Hoebeke, Piet, Lumen, Nicolaas, Poelaert, Filip, Rottey, Sylvie, Van Belle, Simon, Van Praet, Charles, Vermassen, Tijl   +8 more
core   +2 more sources

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Investigation Into the Dynamics of the Cupula in the Vestibular Organ of Adult Zebrafish Using Metabolic Glycoengineering

Angewandte Chemie, EarlyView.
The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer, Andrea Jüngst, Verena F. Schöwe, Anne‐Katrin Gronewald, Valentin Wittmann   +4 more
wiley   +2 more sources