Results 191 to 198 of about 13,352,036 (198)

Precision Imprinting of Glycopeptides for Facile Preparation of Glycan-Specific Artificial Antibodies.

Analytical Chemistry, 2018
Antibodies specific to glycans are essential in many areas for many important fields, including disease diagnostics, therapeutics, and fundamental researches. However, due to their low immunogenicity and poor availability, glycans pose serious challenges
Zijun Bie, Rongrong Xing, Xinpei He, Yanyan Ma, Yang Chen, Zhen Liu   +5 more
semanticscholar   +1 more source

An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.

Journal of the American Chemical Society, 2012
Protein endoglycosidases are useful for biocatalytic alteration of glycans on protein surfaces, but the currently limited selectivity of endoglycosidases has prevented effective manipulation of certain N-linked glycans widely found in nature.
J. Goodfellow, Kavitha Baruah, Keisuke Yamamoto, Camille Bonomelli, B. Krishna, D. Harvey, M. Crispin, Christopher N. Scanlan, B. G. Davis   +8 more
semanticscholar   +1 more source

Endoglycosidase-mediated incorporation of 18O into glycans for relative glycan quantitation.

Analytical Chemistry, 2011
Stable isotopic labeling coupled with mass spectrometry analysis is a promising method of detecting quantitative variations in glycans, which may result in aberrant glycosylation in many disorders and diseases.
Wei Zhang, Hong Wang, Hailin Tang, Pengyuan Yang   +3 more
semanticscholar   +1 more source

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid.

Arthritis & Rheumatism, 2010
OBJECTIVE Anti-citrullinated protein antibodies (ACPA) exhibit unique specificity for rheumatoid arthritis. However, it is incompletely understood whether and how ACPA contribute to disease pathogenesis. The Fc part of human IgG carries 2 N-linked glycan
H. Scherer, D. van der Woude, A. Ioan-Facsinay, H. el Bannoudi, L. Trouw, Jun Wang, T. Häupl, G. Burmester, A. Deelder, T. Huizinga, M. Wuhrer, R. Toes   +11 more
semanticscholar   +1 more source

Enrichment of glycopeptides for glycan structure and attachment site identification

Nature Methods, 2009
J. Nilsson, U. Rüetschi, Adnan Halim, C. Hesse, Elisabet Carlsohn, G. Brinkmalm, G. Larson   +6 more
semanticscholar   +1 more source

A Novel Role for the IgG Fc Glycan: The Anti-inflammatory Activity of Sialylated IgG Fcs

Journal of Clinical Immunology, 2010
R. Anthony, J. Ravetch
semanticscholar   +1 more source

Novel roles for the IgG Fc glycan

Annals of the New York Academy of Sciences, 2012
R. Anthony, F. Wermeling, J. Ravetch
semanticscholar   +1 more source

Conformation and function of the N-linked glycan in the adhesion domain of human CD2

Science, 1995
Daniel F. Wyss, Johnathan S. Choi, Jing Li, M. Knoppers, Kevin J. Willis, A. R. Arulanandam, A. Smolyar, E. Reinherz, Gerhard Wagner   +8 more
semanticscholar   +1 more source