Results 211 to 220 of about 13,562,347 (304)

IgG N-Glycan Profiles in Mothers and Infants Postpartum in the Context of Maternal Obesity and Gestational Diabetes. [PDF]

Int J Mol Sci
Farkas A, Matsyura O, Besh L, Guttman A, Vari SG.   +4 more
europepmc   +1 more source

Assessment of Lectin Staining Biomarkers for GNE Myopathy Gene Therapy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims GNE myopathy (GNEM) is a rare, autosomal recessive disorder caused by mutations in the UDP‐N‐acetylglucosamine (GlcNAc) 2‐epimerase/N‐acetylmannosamine (ManNAc) kinase (GNE) gene, which encodes a required enzyme for sialic acid (SA) biosynthesis.
Kristina M. Sattler, Brian J. Paleo, Mackenzie N. Roth, Kara E. Bradley, Megan N. Winkler, Wakako Yoshioka, Ichizo Nishino, Christoph Lepper, Kelly E. Crowe   +8 more
wiley   +1 more source

N-glycan-dependent protein maturation and quality control in the ER. [PDF]

Nat Rev Mol Cell Biol
Guay KP, Chou WC, Canniff NP, Paul KB, Hebert DN.   +4 more
europepmc   +1 more source

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

PNGaseL from <i>Flavobacterium akiainvivens</i> targets a diverse range of N-glycan structures. [PDF]

R Soc Open Sci
Bakshani CR, Urbanowicz PA, Badia Tortosa C, Melo Diaz JM, Kujawska M, Ojuri TO, Hall LJ, Spencer DIR, Bolam DN, Crouch LI.   +9 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza, Mathieu Fanuel, Hélène Rogniaux, David Ropartz   +3 more
wiley   +1 more source

Coregistration of Multimodal Imaging Mass Spectrometry and Optical Images of Tissue Sections at Single‐Cell Resolution

Surface and Interface Analysis, EarlyView.
ABSTRACT Accurate alignment of histopathological structures in optical images and imaging mass spectrometry (IMS) datasets is crucial for providing meaningful biological interpretation. Integrating IMS with optical or other imaging modalities remains challenging due to sample‐preparation constraints, mismatched spatial resolutions, and the need for ...
Ameh Orotomah, Rachel Pryce, Josianne Lefebvre, Raphaël Trouillon, Ludvik Martinu, Pierre Chaurand, Melissa K. Passarelli   +6 more
wiley   +1 more source

The <i>Schizosaccharomyces pombe</i> Glycosyltransferase Gmh5 is a Functional Homologue of the α-1,6-Mannosyltransferase Mnn10 Crucial for N-Glycan Processing. [PDF]

Food Technol Biotechnol
Lommel M, Hutzler F, Siukstaite L, Wild K, Grbavac A, Sinning I, Strahl S.   +6 more
europepmc   +1 more source

Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating

Small, EarlyView.
Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim, Lingqing Zong, Wei Deng, Maria Kavallaris, Zi Gu   +4 more
wiley   +1 more source