VIEW, EarlyView.2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu +11 more
wiley +1 more source
Oxidative stress‐driven metabolic reprogramming defines two subtypes of cutaneous melanoma
VIEW, EarlyView.Cutaneous melanoma exhibits substantial molecular heterogeneity, and metabolic reprogramming may contribute to differences in tumor behavior and treatment response. In this study, we integrated multi‐omics data from SKCM cohorts to identify two metabolism‐associated subtypes with distinct oxidative stress profiles, immune microenvironments, prognostic ...
Qikun Gao, Ziyi Liu, Ying Xu
wiley +1 more source
Toti-N-glycan Recognition Enables Universal Multiplexed Single-Nucleus RNA Sequencing. [PDF]
Research (Wash D C)Guo Y +12 more
europepmc +1 more source
Biology, ecology, and conservation of the Italian hare Lepus corsicanus: a review
Wildlife Biology, EarlyView.The Italian hare Lepus corsicanus, an endemic lagomorph of Italy, serves as a critical case study in evolutionary biology and conservation. Once taxonomically debated, modern genetic and morphological analyses confirm its status as a distinct Pleistocene lineage restricted to the central‐southern Italian Peninsula and Sicily.
Pierangelo Freschi, Valter Trocchi
wiley +1 more source
Recent advances in N-glycan biomarker discovery among human diseases. [PDF]
Acta Biochim Biophys Sin (Shanghai)Wang Y, Liu Y, Liu S, Cheng L, Liu X.
europepmc +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Insect Science, EarlyView.Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
Spotlight on Glycan Pairing: The Generation and Impact of Monoclonal Antibody Asymmetrical Fc N‑Glycan Pairs on Fc Receptor Interaction. [PDF]
ACS Pharmacol Transl SciMeudt M +8 more
europepmc +1 more source
Insect Science, EarlyView.This diagram illustrates that the horizontally transferred panBC influences the level and localization of vitellogenin (Vg) by facilitating pantothenate production and juvenile hormone (JH) biosynthesis. In turn, Vg shields symbionts by suppressing autophagic degradation in bacteriocytes.
Xiang Sun +5 more
wiley +1 more source
CRISPR screens and lectin microarrays identify high mannose N-glycan regulators. [PDF]
Nat CommunTsui CK +10 more
europepmc +1 more source
A multi-analyte liquid biopsy approach for nonseminomatous testicular germ cell tumors: combining cfDNA and N-glycan analysis in blood and seminal plasma. [PDF]
Cancer Cell IntKrasic J +14 more
europepmc +1 more source