Results 191 to 200 of about 95,722 (299)

N-glycan structures of β-HlH subunit of Helix lucorum hemocyanin [PDF]

, 2017
Devreese, Bart, Dolashka, Pavlina, Van Beeumen, Jozef, Velkova, Lyudmila   +3 more
core   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Mass spectrometry imaging reveals alterations in protein and N-glycan molecular signatures in endometriosis tissues. [PDF]

Anal Bioanal Chem
Lin M, Seeley EH, Ledet S, Salazar C, Breen MT, Eberlin LS.   +5 more
europepmc   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Spatial N-glycan rearrangement on α₅β₁ integrin nucleates galectin-3 oligomers to determine endocytic fate. [PDF]

Nat Commun
Shafaq-Zadah M, Dransart E, Hamitouche I, Wunder C, Chambon V, Valades-Cruz CA, Leconte L, Sarangi NK, Robinson J, Bai SK, Regmi R, Di Cicco A, Hovasse A, Bartels R, Nilsson UJ, Cianférani-Sanglier S, Leffler H, Keyes TE, Lévy D, Raunser S, Roderer D, Johannes L.   +21 more
europepmc   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Crystal structure of the fungal mannosyltransferase Och1 reveals active site primed for N-glycan binding. [PDF]

PLoS One
Kelly ETR, Rodionov D, Sleno B, Romero PA, Berghuis AM.   +4 more
europepmc   +1 more source

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Selective bioorthogonal probe for N-glycan hybrid structures. [PDF]

Nat Chem Biol
Mukherjee MM, Biesbrock D, Abramowitz LK, Pavan M, Kumar B, Walter PJ, Azadi P, Jacobson KA, Hanover JA.   +8 more
europepmc   +1 more source