Results 261 to 270 of about 13,562,347 (304)

N-glycan structures: recognition and processing in the ER

Trends in Biochemical Sciences, 2010
The processing of N-linked glycans determines secretory protein homeostasis in the eukaryotic cell. Folding and degradation of glycoproteins in the endoplasmic reticulum (ER) are regulated by molecular chaperones and enzymes recruited by specific oligosaccharide structures.
Aebi Markus, Bernasconi Riccardo, Clerc Simone, Molinari Maurizio   +3 more
openaire   +3 more sources

N-glycan terocessing in the ER

1994
Abstract N-linked oligosaccharide synthesis begins with the transfer of a precursor oligosaccharide from a dolichol-P-P-linked intermediate to Asn-X-Ser/Thr. This oligosaccharide, Glc3Man9GlcNAc2, in most cells is then trimmed by a-glucosidases and a,-mannosidases, beginning in the ER.
R Trimbe, K Morcrnen,, A Herscovics
openaire   +1 more source

Review/N-glycans: The making of a varied toolbox

Plant Science, 2015
Asparagine (N)-linked protein glycosylation is one of the most crucial, prevalent, and complex co- and post-translational protein modifications. It plays a pivotal role in protein folding, quality control, and endoplasmic reticulum (ER)-associated degradation (ERAD) as well as in protein sorting, protein function, and in signal transduction ...
Nausicaä, Lannoo, Els J M, Van Damme
openaire   +2 more sources

Permethylated N-Glycan Analysis with Mass Spectrometry

2013
Protein glycosylation plays an important role in multiple cell functions, and aberrations of protein glycosylation are associated with various malignancies including cancer. In this chapter, we provide a detailed protocol for MALDI MS analysis of permethylated N-glycans extracted from human serum proteins.
Zhenxin, Lin, David M, Lubman
openaire   +2 more sources

N-Glycans and Diabetes

2023
Tamara Štambuk, Gordan Lauc
openaire   +1 more source

Automated Glycan Assembly of 19F-labeled Glycan Probes Enables High-Throughput NMR Studies of Protein–Glycan Interactions

Angewandte Chemie - International Edition, 2021
Giulio Fittolani, Christoph Rademacher, Martina Delbianco   +2 more
exaly  

N-Glycans

2023
openaire   +1 more source

N-Glycan biosynthesis

Reactome - a curated knowledgebase of biological pathways, 2010
G Dall'Olio, P Gagneux
openaire   +1 more source

Glycan Labeling and Analysis in Cells and In Vivo

Annual Review of Analytical Chemistry, 2021
Qi Tang, Xing Chen
exaly  

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

Cell, 2021
Richard Laga, Hui Li, Kevin O Saunders
exaly