Results 281 to 290 of about 13,066,219 (329)

LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping. [PDF]

J Biol Chem
Tokoro Y, Nagae M, Nakano M, Harduin-Lepers A, Kizuka Y.   +4 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level. [PDF]

Nat Commun
Godbole S, Voß H, Gocke A, Schlumbohm S, Schumann Y, Peng B, Mynarek M, Rutkowski S, Dottermusch M, Dorostkar MM, Korshunov A, Mair T, Pfister SM, Kwiatkowski M, Hotze M, Neumann P, Hartmann C, Weis J, Liesche-Starnecker F, Guan Y, Moritz M, Siebels B, Struve N, Schlüter H, Schüller U, Krisp C, Neumann JE.   +26 more
europepmc   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate. [PDF]

Nat Commun
Sastre DE, Sultana N, V A S Navarro M, Huliciak M, Du J, Cifuente JO, Flowers M, Liu X, Lollar P, Trastoy B, Guerin ME, Sundberg EJ.   +11 more
europepmc   +1 more source

Serum <i>N</i>-Glycan Profiling Identifies Candidate Glycan Biomarkers for Early Detection and Prediction of Alzheimer's Disease. [PDF]

J Proteome Res
Onigbinde S, Solomon J, Gutierrez-Reyes CD, Daramola O, Fowowe M, Adeniyi M, DuBois KN, Bakulski KM, Kanaan NM, Lubman DM, Mechref Y.   +10 more
europepmc   +1 more source

N-glycan biosignatures as a potential diagnostic biomarker for early-stage pancreatic cancer. [PDF]

World J Gastrointest Oncol
Wen YR, Lin XW, Zhou YW, Xu L, Zhang JL, Chen CY, He J.   +6 more
europepmc   +1 more source

N-glycan profiling of tissue samples to aid breast cancer subtyping. [PDF]

Sci Rep
Benesova I, Nenutil R, Urminsky A, Lattova E, Uhrik L, Grell P, Kokas FZ, Halamkova J, Zdrahal Z, Vojtesek B, Novotny MV, Hernychova L.   +11 more
europepmc   +1 more source

Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI. [PDF]

Cancer Res Commun
Hartig JP, Bejar K, Young LEA, Grimsley G, Bethard JR, Troyer DA, Hernandez J, Wu JD, Ippolito JE, Ball LE, Gelfond JAL, Johnson-Pais TL, Mehta AS, Leach RJ, Angel PM, Drake RR.   +15 more
europepmc   +1 more source