Results 41 to 50 of about 31,604 (216)

Active-site motifs of lysosomal acid hydrolases: invariant features of clan GH-A glycosyl hydrolases deduced from hydrophobic cluster analysis.

Glycobiology, 1997
The clan GH-A is a group of more than 200 proteins representing nine established families of glycosyl hydrolases that act on a large variety of substrates.
P. Durand, P. Lehn, I. Callebaut, S. Fabrega, B. Henrissat, J. Mornon   +5 more
semanticscholar   +1 more source

Molecular Characterization of an Endo-β-1,4-Glucanase, CelA_J93, from the Recently Isolated Marine Bacterium, Cellulophaga sp. J9-3

Applied Sciences, 2019
A novel cellulase was characterized from a newly isolated marine bacterium, strain J9-3. Phylogenetic analysis based on the 16S rRNA gene revealed that strain J9-3 belonged to the genus Cellulophaga, and thus, it was named Cellulophaga sp. J9-3.
Da Som Kim, Won-Jae Chi, Soon-Kwang Hong   +2 more
doaj   +1 more source

Diffusion-based Molecule Generation with Informative Prior Bridges [PDF]

arXiv, 2022
AI-based molecule generation provides a promising approach to a large area of biomedical sciences and engineering, such as antibody design, hydrolase engineering, or vaccine development. Because the molecules are governed by physical laws, a key challenge is to incorporate prior information into the training procedure to generate high-quality and ...
arxiv  

Replacement of the Catalytic Nucleophile Aspartyl Residue of Dextran Glucosidase by Cysteine Sulfinate Enhances Transglycosylation Activity [PDF]

, 2013
Dextran glucosidase from Streptococcus mutans (SmDG) catalyzes the hydrolysis of an α-1,6-glucosidic linkage at the nonreducing end of isomaltooligosaccharides and dextran.
Kimura, Atsuo, Kobayashi, Momoko, Mori, Haruhide, Okuyama, Masayuki, Saburi, Wataru   +4 more
core   +1 more source

Functional characterization of cellulases identified from the cow rumen fungus Neocallimastix patriciarum W5 by transcriptomic and secretomic analyses

Biotechnology for Biofuels, 2011
Background Neocallimastix patriciarum is one of the common anaerobic fungi in the digestive tracts of ruminants that can actively digest cellulosic materials, and its cellulases have great potential for hydrolyzing cellulosic feedstocks.
Wang Tzi-Yuan, Chen Hsin-Liang, Lu Mei-Yeh J, Chen Yo-Chia, Sung Huang-Mo, Mao Chi-Tang, Cho Hsing-Yi, Ke Huei-Mien, Hwa Teh-Yang, Ruan Sz-Kai, Hung Kuo-Yen, Chen Chih-Kuan, Li Jeng-Yi, Wu Yueh-Chin, Chen Yu-Hsiang, Chou Shao-Pei, Tsai Ya-Wen, Chu Te-Chin, Shih Chun-Chieh A, Li Wen-Hsiung, Shih Ming-Che   +20 more
doaj   +1 more source

Enzyme Similarity Networks [PDF]

arXiv, 2022
There is a crescent use of enzymes in multiple industries and sciences, ranging from materials and fuel synthesis to pharmaceutical and food production. Their applicability in this variety of fields depends not only on their biochemical function but also on their physicochemical properties.
arxiv  

A Synthetic Glycan Microarray Enables Epitope Mapping of Plant Cell Wall Glycan-Directed Antibodies [PDF]

, 2017
In the last three decades, more than 200 monoclonal antibodies have been raised against most classes of plant cell wall polysaccharides by different laboratories worldwide.
Andersen, MCF, Bartetzko, MP, Boos, I, Clausen, MH, Dallabernadina, P, Hahn, MG, Knox, JP, Kotake, T, Pfrengle, F, Ruprecht, C, Senf, D   +10 more
core   +2 more sources

Prebiotic Oligosaccharides Potentiate Host Protective Responses against L. Monocytogenes Infection. [PDF]

, 2017
Prebiotic oligosaccharides are used to modulate enteric pathogens and reduce pathogen shedding. The interactions with prebiotics that alter Listeria monocytogenes infection are not yet clearly delineated. L.
Chen, Poyin, Huang, Bihua, Kong, Nguyet, Reiter, Taylor, Weimer, Bart C   +4 more
core   +3 more sources

A broad pH range and processive chitinase from a metagenome library

Brazilian Journal of Medical and Biological Research
Chitinases are hydrolases that degrade chitin, a polymer of N-acetylglucosamine linked β(1-4) present in the exoskeleton of crustaceans, insects, nematodes and fungal cell walls.
S.S. Thimoteo, A. Glogauer, H. Faoro, E.M. de Souza, L.F. Huergo, B.M. Moerschbacher, F.O. Pedrosa   +6 more
doaj   +1 more source

Representing catalytic mechanisms with rule composition [PDF]

arXiv, 2022
Reaction mechanisms are often presented as sequences of elementary steps, such as codified by arrow pushing. We propose an approach for representing such mechanisms using graph transformation. In this framework, each elementary step is a rule for modifying a molecular graph and a mechanism is a sequence of such rules.
arxiv