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Neuropathy in n-hexane poisoning

S.S. Korsakov Journal of Neurology and Psychiatry
N-Hexane is a solvent widely used in manufacturing as a cleaner, degreaser and component of rubber cement. Chronic exposure to n-hexane either through contact with unprotected skin or inhalation can lead to the development of clinical symptoms and electrophysiological changes similar to those of inflammatory demyelinating polyneuropathy which requires ...
E.S. Druzhinina   +8 more
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n-Hexane induces Parkinsonism in rodents

Brain Research, 1990
A case of human parkinsonism, due to n-hexane exposure, was recently described. On the basis of this observation, we treated mice and rats with n-hexane and its principle toxic metabolite 2,5-hexanedione. The mice underwent a chronic treatment intraperitoneum, the rats were treated stereotaxically into the substantia nigra.
G, Pezzoli   +4 more
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Effect of methanol on the biofiltration of n-hexane

Journal of Hazardous Materials, 2012
This study investigated the removal of recalcitrant compounds in the presence of a hydrophilic compound. n-Hexane is used as a model compound to represent hydrophobic compounds. Methanol has been introduced in mixture with n-hexane in order to increase the bioavailability of n-hexane in trickle-bed-air-biofilters (TBABs). The mixing ratios investigated
Abderrahman, Zehraoui   +2 more
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n‐Hexane‐induced parkinsonism: Pathogenetic hypotheses

Movement Disorders, 1995
Abstractn‐Hexane, similar hydrocarbons, and derivatives are common environmental pollutants and by‐products of lipid peroxidation, and they may have a nigrotoxic effect like that of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine. This report describes our second case of parkinsonism in a subject exposed to n‐hexane.
Pezzoli G   +8 more
openaire   +4 more sources

Poor metabolization of n-hexane in Parkinson's disease

Journal of Neurology, 2003
Although genomic screening studies have identified several genes associated with Parkinson's disease (PD), there is evidence that environmental factors are also involved in the pathogenesis of the disease and that hydrocarbon-solvents may be one of them. The genetic component is less evident in late-onset PD. To assess whether age and PD may affect the
M. Canesi   +6 more
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N-Hexane Neuropathy

New England Journal of Medicine, 1971
Abstract In three adult cabinet finishers weakness and sensory loss developed as a result of prolonged and intense exposure to an industrial solvent. After leaving this employment, they improved. Analysis of the immediate environment and solvent revealed that each worker had an oral, respiratory and dermal contact with toxic levels of n-hexane ...
A, Herskowitz, N, Ishii, H, Schaumburg
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n-Hexane Polyneuropathy in Japan: A Review of n-Hexane Poisoning and Its Preventive Measures

Environmental Research, 1993
n-Hexane is used in industry as a solvent for adhesive, dry cleaning, and vegetable oil extraction. In 1963, the first case of severe polyneuropathy suspected to be caused by n-hexane was referred to us. Case studies, animal experiments, and field surveys on n-hexane poisoning were conducted, and preventive measures like threshold limit value revision ...
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Avalanche breakdown in n-hexane

Journal of Physics D: Applied Physics, 1979
Time lags to breakdown in n-hexane have been measured in high over-voltages, using approximately 100 ns width rectangular pulses. At a constant field, the time lags are divided into two types, N and B, at a 'critical distance' d. Above dc, Laue plots have almost similar kinked-line characteristics; below dc, a straight line is obtained.
K Arii, S Kitani, M Kawamura
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Particles and pulses in n-hexane

Journal of Electrostatics, 1979
Abstract By experimental observation the persistent controversy about the order of charge carried by minute natural particles in a liquid dielectric is resolved. The work reported earlier has been extended, by use of the on-line transient recorder in a dual channel mode, to provide a clear demonstration that the fempto-Coulomb pulses of conduction ...
C.J. Buffam, J.E. Brignell
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The photochemical sulphoxidation of n-hexane

Tetrahedron, 1965
Abstract The photochemical sulphoxidation of n-hexane in the presence of acetic anhydride giving hexanesulphonic acid has been examined. A maximum yield of 26% is obtained when the sulphoxidation is carried out with a molar ratio of n-hexane:acetic anhydride of 19:1. An increase in the reaction temperature of 28° serves to increase the yield, and for
Y. Ogata, Y. Izawa, T. Tsuda
openaire   +1 more source

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