Results 1 to 10 of about 4,524 (100)

A case report of anti-N-methyl-ᴅ-aspartate receptor encephalitis: prioritizing clinical symptoms over diagnostic test results [PDF]

open access: yesEncephalitis
Anti-N-methyl-ᴅ-aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis; however, the frequently negative initial diagnostic test results for NMDAR complicate its diagnosis.
Wankiun Lee
doaj   +2 more sources

N-methylaspartate-activated calcium channels in rat brain cortex slices. Effect of calcium channel blockers and of inhibitory and depressant substances

open access: yesNeuroscience, 1986
N-Methyl-DL-aspartate, L-glutamate, kainate and DL-homocysteate were found to increase the initial rate and the maximal uptake of 45Ca into the non-inulin space of rat brain cortex slices incubated in vitro. The N-methylaspartate-stimulated calcium uptake was blocked by cadmium and cobalt ions, but not by the organic calcium channel blocker nifedipine ...
F Orrego
exaly   +4 more sources

Clinical characteristics of patients with anti⁃myelin oligodendrocyte glycoprotein⁃IgG associated disorders complicated with antibody overlap syndrome

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To summarize the clinical characteristics of anti⁃myelin oligodendrocyte glycoprotein⁃IgG associated disorders (MOGAD) complicated with antibody overlap syndrome.
QIN Jing⁃jing   +5 more
doaj   +1 more source

Antagonism of N‐methylaspartate and synaptic responses of neurones in the rat ventrobasal thalamus by ketamine and MK‐801 [PDF]

open access: yesBritish Journal of Pharmacology, 1988
Extracellular single neurone recordings were made in the ventrobasal thalamus of urethaneanaesthetized rats. Iontophoretically and intravenously administered ketamine and MK‐801 were found to be selective antagonists of responses of neurones to iontophoretically applied N‐methylaspartate.
T E, Salt, D G, Wilson, S K, Prasad
openaire   +2 more sources

The role of N‐methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli. [PDF]

open access: yesThe Journal of Physiology, 1987
1. Single‐cell recordings were made from neurones in various spinal laminae in anaesthetized or decerebrated, spinalized or intact rats and cats. Cells were activated by controlled peripheral sensory stimuli which mimicked natural conditions and with some cells also by micro‐electrophoretically administered excitatory amino acid analogues.
P M, Headley, C G, Parsons, D C, West
openaire   +2 more sources

Effect of flupirtine on the growth and viability of U373 malignant glioma cells

open access: yesCancer Biology & Medicine, 2013
Objective:Flupirtine is a non-opioid analgesic without antipyretic or antiphlogistic properties but with favorable tolerability in humans. This analgesic also exhibits neuroprotective activities.
Elango Panchanathan   +2 more
doaj   +1 more source

Neuroprotective role of acamprosate and rasagiline in epilepsy: In silico and in vivo study [PDF]

open access: yesScripta Medica
Background/Aim: Current treatments for epilepsy have only indicative relief without smashing the pathological trademarks of the disease. The unmet need is to find new therapeutic active drug candidates for effective management of epilepsy and associated ...
Kumar Sandeep   +7 more
doaj   +1 more source

Encefalitis autoinmunitaria asociada a anticuerpos contra el receptor N-metil-D-aspartato: presentación de dos casos

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
La encefalitis asociada a anticuerpos contra receptores N-metil-D-aspartato es un síndrome neurológico que se presenta más comúnmente en mujeres jóvenes y frecuentemente se asocia al teratoma de ovario.
José Bustos   +5 more
doaj   +1 more source

A magnesium‐sensitive post‐synaptic potential in rat cerebral cortex resembles neuronal responses to N‐methylaspartate. [PDF]

open access: yesThe Journal of Physiology, 1986
In isolated slices of rat cerebral cortex, intracellular recordings were obtained from pyramidal cells that were predominantly in layers II/III. These cells could be antidromically activated from the underlying white matter and had resting potentials of greater than ‐75 mV, action potentials with amplitudes of greater than 70 mV (measured from ...
openaire   +2 more sources

Evaluation of the Interaction between NMDA Receptors of Nucleus Accumbens and Muscarinic Receptors in Memory

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2013
Background and Objectives: Whereas studies have indicated the interaction between NMDA and cholinergic systems, this study was performed with the aim of determining the role of NMDA receptors in the nucleus accumbens (NAc) in scopolamine-induced amnesia.
Bahareh Pakpour   +4 more
doaj   +2 more sources

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