N-methylaspartate-activated calcium channels in rat brain cortex slices. Effect of calcium channel blockers and of inhibitory and depressant substances [PDF]
Neuroscience, 1986 N-Methyl-DL-aspartate, L-glutamate, kainate and DL-homocysteate were found to increase the initial rate and the maximal uptake of 45Ca into the non-inulin space of rat brain cortex slices incubated in vitro. The N-methylaspartate-stimulated calcium uptake was blocked by cadmium and cobalt ions, but not by the organic calcium channel blocker nifedipine ...
F Orrego
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A case report of anti-N-methyl-ᴅ-aspartate receptor encephalitis: prioritizing clinical symptoms over diagnostic test results [PDF]
EncephalitisAnti-N-methyl-ᴅ-aspartate receptor (NMDAR) encephalitis is the most common type of autoimmune encephalitis; however, the frequently negative initial diagnostic test results for NMDAR complicate its diagnosis.
Wankiun Lee
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Antagonism of N‐methylaspartate and synaptic responses of neurones in the rat ventrobasal thalamus by ketamine and MK‐801 [PDF]
British Journal of Pharmacology, 1988 Extracellular single neurone recordings were made in the ventrobasal thalamus of urethaneanaesthetized rats. Iontophoretically and intravenously administered ketamine and MK‐801 were found to be selective antagonists of responses of neurones to iontophoretically applied N‐methylaspartate.
T E, Salt, D G, Wilson, S K, Prasad
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Amantadine Attenuates Secondary Oxidative and Inflammatory Injury by Modulating the HIF-1α/BNIP3L/HMGB1 Axis in Rat Model of Traumatic Brain Injury [PDF]
MedicinaBackground and Objectives: Traumatic brain injury (TBI) triggers oxidative stress, mitochondrial dysfunction, and sterile inflammation. Amantadine (ATD), a weak NMDA receptor antagonist, has shown neuroprotective potential, but its mechanistic basis ...
Ahmet Bindal +7 more
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Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Objective To summarize the clinical characteristics of anti⁃myelin oligodendrocyte glycoprotein⁃IgG associated disorders (MOGAD) complicated with antibody overlap syndrome.
QIN Jing⁃jing +5 more
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The role of N‐methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli. [PDF]
The Journal of Physiology, 1987 1. Single‐cell recordings were made from neurones in various spinal laminae in anaesthetized or decerebrated, spinalized or intact rats and cats. Cells were activated by controlled peripheral sensory stimuli which mimicked natural conditions and with some cells also by micro‐electrophoretically administered excitatory amino acid analogues.
P M, Headley, C G, Parsons, D C, West
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Effect of flupirtine on the growth and viability of U373 malignant glioma cells
Cancer Biology & Medicine, 2013 Objective:Flupirtine is a non-opioid analgesic without antipyretic or antiphlogistic properties but with favorable tolerability in humans. This analgesic also exhibits neuroprotective activities.
Elango Panchanathan +2 more
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Neuroprotective role of acamprosate and rasagiline in epilepsy: In silico and in vivo study [PDF]
Scripta MedicaBackground/Aim: Current treatments for epilepsy have only indicative relief without smashing the pathological trademarks of the disease. The unmet need is to find new therapeutic active drug candidates for effective management of epilepsy and associated ...
Kumar Sandeep +7 more
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Biomédica: revista del Instituto Nacional de Salud, 2017 La encefalitis asociada a anticuerpos contra receptores N-metil-D-aspartato es un síndrome neurológico que se presenta más comúnmente en mujeres jóvenes y frecuentemente se asocia al teratoma de ovario.
José Bustos +5 more
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A magnesium‐sensitive post‐synaptic potential in rat cerebral cortex resembles neuronal responses to N‐methylaspartate. [PDF]
The Journal of Physiology, 1986 In isolated slices of rat cerebral cortex, intracellular recordings were obtained from pyramidal cells that were predominantly in layers II/III. These cells could be antidromically activated from the underlying white matter and had resting potentials of greater than ‐75 mV, action potentials with amplitudes of greater than 70 mV (measured from ...
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