Results 151 to 160 of about 94,964 (227)

Clinicopathological characteristics, genetic aberrations, and optimized treatment strategies in double-hit and triple-hit lymphoma: a multi-center cohort study. [PDF]

Mol Biomed
Shen YG, Ji MM, Shi Q, Wei XL, Fan L, Liu TB, Liu Y, Dong LH, Liang AB, Huang L, Zhou H, Huang HH, Yang SM, Wang XB, Tian YY, Zhu ZM, Bai O, Li F, Shi WY, Xu B, Wang X, Shi KQ, Tang W, Yi HM, Chen SY, Zheng Z, Cheng S, Xu PP, Zhao WL, Wang L.   +29 more
europepmc   +1 more source

Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications

Aggregate, Volume 7, Issue 2, February 2026.
The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed, Abdallah Alhalabi, Didier Gasparutto, Xavier Le Guével   +3 more
wiley   +1 more source

The CCAT2 enigma: pioneering insights into colorectal cancer pathophysiology and therapeutic innovation. [PDF]

Cancer Cell Int
Fathollahzadeh M, Vanan AG, Mohammadmoradi N, Ghorbaninezhad F, Eini P, Tofighi Zavareh MA, Rahmani Y, Rostami S, Tahmasebi S, Safarzadeh E.   +9 more
europepmc   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio, Huijie Yuan, Leandro Raul Soria, Sara Basse Hansen, Iolanda Boffa, Paola Arena, Benedetta Attianese, Maureen. O'Sullivan, Noelle Cullinan, Lewis Pang, Daan Marinus Ferdinand van Aalten, Nicola Brunetti‐Pierri, Sally Ann Lynch   +12 more
wiley   +1 more source

Long noncoding RNA-dependent control of Myc transcriptional bursting. [PDF]

Cell Rep
Li Q, Dilsavor C, Gahramanov V, Floyd E, Ding J, Glynn JJ, Chiotakakos I, Olivero CE, Zamudio JR, Dimitrova N.   +9 more
europepmc   +1 more source

A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava, Sudhakar Venkatesh, Michael S. Torbenson, Patrick S. Kamath, Moira Hilscher   +4 more
wiley   +1 more source

Targeting c-Myc-p300-CARM1 complex induces ferroptosis and reduces CD8⁺ T cell exhaustion in esophageal squamous cell carcinoma. [PDF]

Int J Biol Sci
Wang Y, Li Y, Ren G, Zhou J, Chen W, Zhang K, Yu X, Yin Y, Cong J, Ma L, Zheng X, Zhao Y, Liu Z.   +12 more
europepmc   +1 more source

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

Cancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa, N. D. Amal Wageesha, Sameera R. Samarakoon, Sagarika Ekanayake, H. M. Kasuni Akalanka   +4 more
wiley   +1 more source

The long non-coding RNA UGDH-AS1 encodes an NK-cell-inhibiting micropeptide in triple-negative breast cancers. [PDF]

Nat Commun
Zhang Z, Li F, Dai X, Deng J, Guo B, Wang Y, Liu W, Pan Y, Zhao T, Wang S, Li W, Jin C, Zhang H, Zhang S, Zhou Y.   +14 more
europepmc   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source