Results 181 to 190 of about 94,964 (227)

A case of primary cutaneous diffuse large B-cell lymphoma, leg type with <i>MYC</i> rearrangement and high BCL2 protein expression due to trisomy 18. [PDF]

Nagoya J Med Sci
Matsui Y, Katsumi A, Tanaka K, Ohara F, Motegi K, Abe A, Tamura S, Yamamoto K, Matsushita T, Adachi M, Nagata Y, Hasegawa M.   +11 more
europepmc   +1 more source

Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment

SmartMat, Volume 7, Issue 1, February 2026.
Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova, Ioannis Iliadis, Malamati Poimenidou, Chrysi Patsidou, Maria Zafeiriou‐Chatziefraimidou, Diamantis D. Almaliotis, Ioannis T. Tsinopoulos, Ivan V. Zelepukin, Alexey V. Yaremenko   +8 more
wiley   +1 more source

Plakophilin 1 in cancer: context-dependent dualism, subcellular dynamics, and therapeutic targeting. [PDF]

Front Cell Dev Biol
Huang YM, Zhang WL, Tang FQ.
europepmc   +1 more source

PA2G4 Functions as a Cofactor for MYC Family Oncoproteins in MYC-Driven Malignancies. [PDF]

Cells
Krishan S, Koach J, Lim T, Yeo K, Cheong F, Luo JS, Massudi H, Gao X, Heangsarath S, Kueh AJ, Herold MJ, Cheung BB, Marshall GM.   +12 more
europepmc   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, Volume 117, Issue 2, Page 297-307, February 2026.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

Treatment outcomes of zanubrutinib-based regimen in newly diagnosed patients with MYC/BCL2 double-expressor diffuse large B-cell lymphoma: a retrospective multicenter real-world study. [PDF]

Ann Hematol
Lu B, Wang Y, Jin M, Zhang J, Xu X, Zeng Y, Zhao L, Wang H.   +7 more
europepmc   +1 more source

A YAP/TAZ–CDC6 Axis Initiates and Maintains Malignant Transformation

Cancer Science, Volume 117, Issue 2, Page 353-363, February 2026.
This study demonstrates that constitutive activation of YAP or TAZ is sufficient to induce and maintain malignant transformation in fibroblasts, identifying them as essential oncogenic drivers. Transcriptomic and functional analyses revealed CDC6 as a critical downstream effector of YAP/TAZ, with elevated expression linked to tumorigenesis across ...
David Nduru, Yudai Ohta, Akihiro Nita, Mayumi Niimura, Samson Ngurari, Toshiro Moroishi   +5 more
wiley   +1 more source

The m6A reader YTHDF1 facilitates nasopharyngeal carcinoma proliferation and migration via c-MYC. [PDF]

J Biol Chem
Han P, Xiao Z, Xia T, Wu T, Li S, Ye Y, Zeng H, Zeng M, Zhong Q, Huang X.   +9 more
europepmc   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Evaluating valaciclovir, letermovir, and maribavir safety in first-trimester human placental development. [PDF]

Sci Rep
Atukorala I, de Alwis N, Beard S, Raghavan S, Hannan NJ, Hui L.   +5 more
europepmc   +1 more source