Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Population-wide introduction of dose-adjusted EPOCH-R in high-grade B-cell lymphoma with MYC/BCL2 rearrangements, DLBCL morphology. [PDF]
Alduaij W +18 more
europepmc +1 more source
Amino acid metabolic reprogramming: future prospects for cholangiocarcinoma therapy. [PDF]
Hua S +8 more
europepmc +1 more source
Targeting menin in lysine methyltransferase 2A/nucleophosmin-mutated leukemia: A novel strategy from epigenetic dysregulation to clinical therapy (Review). [PDF]
Bi J, Zhou H.
europepmc +1 more source
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma. [PDF]
Maphutha J +5 more
europepmc +1 more source
The dual fate of DYRK2 in cancer: balancing the light and dark side of tumorigenesis. [PDF]
Suanes-Cobos L +4 more
europepmc +1 more source
Cytogenetic and molecular characterization of an atypical ETP-ALL case with BCL2 dependency: therapeutic implications for Venetoclax use. [PDF]
Gigliotti F +14 more
europepmc +1 more source
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