Results 91 to 100 of about 45,542 (259)

Characterization of the Human Blood Group Glycosyltransferases GTA and GTB for the Synthesis of Blood Group Antigens

Advanced Synthesis &Catalysis, Volume 368, Issue 8, 15 April 2026.
This study presents the highly efficient heterologous production of the human blood group glycosyltransferases GTA/R176A and GTB, along with their comprehensive biochemical and kinetic characterization. Tailored enzyme cascades, involving the bacterial fucosyltransferase FutC and GTA or GTB, generate milligram quantities of various blood group ABH ...
Katja Pöstges, Philip Palm, Kai P. Hussnaetter, Eliška Filipová, Helena Pelantová, Lucie Petrásková, Pavla Bojarová, Vladimír Křen, Lothar Elling   +8 more
wiley   +1 more source

PorA typing of Neisseria meningitidis isolates from Iranian children for vaccine design

Vaccine Research, 2018
Introduction: As the causative agent of meningitis, Neisseria meningitidis has different serogroups. The purpose of this study was to investigate the molecular properties of N. meningitidis strains among Iranian cases. Methods: 450 samples were collected
P Afrough, M Vosogh, MR Asadi Karam, A Behrouzi, G Mardani, SD Siadat   +5 more
doaj  

Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent

Journal of Immunology Research, 2019
Meningococcal disease such as sepsis and meningitidis is hallmarked by an excessive inflammatory response. The causative agent, Neisseria meningitidis, expresses the endotoxin lipooligosaccharide (LOS) that is responsible for activation of immune cells ...
Berhane Asfaw Idosa, Anne Kelly, Susanne Jacobsson, Isak Demirel, Hans Fredlund, Eva Särndahl, Alexander Persson   +6 more
doaj   +1 more source

Polyhydroxyalkanoate beads as a particulate vaccine against Streptococcus pneumoniae and Neisseria meningitidis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand [PDF]

, 2017
Listed in 2018 Dean's List of Exceptional ThesesStreptococcus pneumoniae and Neisseria meningitidis are the major causes of pneumonia and meningitis, respectively, worldwide.
González Miró, Majela
core  

Invasive meningococcal disease in the Veneto region of Italy: A capture-recapture analysis for assessing the effectiveness of an integrated surveillance system [PDF]

, 2017
open8noBACKGROUND: Epidemiology of Neisseria meningitidis has been changing since the introduction of universal vaccination programmes against meningococcal serogroup C (MenC) and meningococcal serogroup B (MenB) has now become dominant.
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Cocchio, Silvia, Furlan, Patrizia, Lazzari, Roberta, Russo, Francesca, Saia, Mario   +7 more
core   +1 more source

Lack of association between vaccine‐induced immune thrombocytopenia and thrombosis and HLA loci in a large cohort

British Journal of Haematology, EarlyView.
Linda Schönborn, Ana Tzvetkova, Thomas Thiele, Uwe Völker, Sabine Ameling, Sören Franzenburg, Lars Kaderali, Andreas Greinacher   +7 more
wiley   +1 more source

Multienzyme Platform for the Synthesis of UDP Sugars and Human Milk Oligosaccharides

ChemBioChem, Volume 27, Issue 8, April 2026.
Engineered Escherichia coli produces six enzymes (UMPK, PPK3, GALK, NAHK, GALU, PPA) that are purified and used in a cell‐free cascade to synthesize UDP‐N‐acetylglucosamine (UDP‐GlcNAc) and UDP‐galactose (UDP‐Gal) from inexpensive substrates. The cascades can be coupled with glycosyltransferases for in situ nucleotide sugar regeneration, enabling ...
Tuan Son Hoang, Fabian Lange, Sebastian Bruno Kleeberg, Lea Thomas, Nam-Hai Hoang, Udo Reichl, Thomas F. T. Rexer   +6 more
wiley   +1 more source

A rare case of peripheral facial paralysis associated with meningococcal meningitis - case report [PDF]

Romanian Journal of Pediatrics
Introduction. Meningococcal meningitis is a severe form of bacterial meningitis caused by the bacterium Neisseria meningitidis (N. meningitidis). It is a medical emergency and requires prompt treatment to prevent severe complications or death. Peripheral
Nicoleta-Ana Tomsa, Cristina Oana Marginean, Monica Cucuiet, Lorena Elena Melit   +3 more
doaj   +1 more source

Origin of Neisseria meningitidis clonal complex 4821

Emerging Microbes and Infections
Neisseria meningitidis (N. meningitidis) is the causative agent of human invasive meningococcal disease (IMD). Clonal complex (CC) 4821 is a unique genetic cluster of N.
Zhizhou Tan, Lin Xu, Jie Che, Juan Xu, Li Xu, Hairui Wang, Maojun Zhang, Biao Kan, Jianguo Xu, Zhujun Shao   +9 more
doaj   +1 more source

α-2,3-Sialyltransferase Expression Level Impacts the Kinetics of Lipooligosaccharide Sialylation, Complement Resistance, and the Ability of Neisseria gonorrhoeae to Colonize the Murine Genital Tract

mBio, 2015
Neisseria meningitidis and Neisseria gonorrhoeae modify the terminal lacto-N-neotetraose moiety of their lipooligosaccharide (LOS) with sialic acid. N.
Lisa A. Lewis, Sunita Gulati, Elizabeth Burrowes, Bo Zheng, Sanjay Ram, Peter A. Rice   +5 more
doaj   +1 more source