Results 171 to 180 of about 54,026 (308)

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Investigating N₂ Fixation Using a Bulky Fe(bisphosphine)₂ Framework. [PDF]

Chemistry
Crawford AD, Doyle LR, Horsewill SJ, Myers WK, Scott DJ, Ashley AE.   +5 more
europepmc   +1 more source

UCYN-A/haptophyte symbioses dominate N₂ fixation in the Southern California Current System. [PDF]

ISME Commun, 2021
Turk-Kubo KA, Mills MM, Arrigo KR, van Dijken G, Henke BA, Stewart B, Wilson ST, Zehr JP.   +7 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Electrocatalytic and Photocatalytic N₂ Fixation Using Carbon Catalysts. [PDF]

Nanomaterials (Basel)
Xu C, Su H, Zhao S, Nilghaz A, Tang K, Ma L, Zou Z.   +6 more
europepmc   +1 more source

Chemotaxis may assist marine heterotrophic bacterial diazotrophs to find microzones suitable for N₂ fixation in the pelagic ocean. [PDF]

ISME J, 2022
Hallstrøm S, Raina JB, Ostrowski M, Parks DH, Tyson GW, Hugenholtz P, Stocker R, Seymour JR, Riemann L.   +8 more
europepmc   +1 more source

Pea-barley intercrop N dynamics in farmers fields

, 2001
Knowledge about crop performances in farmers’ fields provides a link between on-farm practice and re-search. Thereby scientists may improve their ability to understand and suggest solutions for the problems facing those who have the responsibility of ...
Peoples, Mark B., Hauggaard-Nielsen, Henrik, Jensen, Erik S., Andersen, Mette K., Nielsen, Anders H.   +4 more
core  

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Fungal parasites infecting N₂-fixing cyanobacteria reshape carbon and N₂ fixation and trophic transfer. [PDF]

Nat Commun
Feuring A, Lawrence CD, Salcedo J, Whitehouse MJ, Vogts A, Zoccarato L, Klawonn I.   +6 more
europepmc   +1 more source

Low-Ammonium Environment Increases the Nutrient Exchange between Diatom-Diazotroph Association Cells and Facilitates Photosynthesis and N₂ Fixation-a Mechanistic Modeling Analysis. [PDF]

Cells, 2022
Gao M, Armin G, Inomura K.
europepmc   +1 more source