Results 151 to 160 of about 17,313 (241)

IGF2BP3 Triggers STAT3 Pathway by Stabilizing SRC RNA in an m6A‐Dependent Manner to Promote Lymphatic Metastasis in LUAD

Cancer Science, Volume 116, Issue 4, Page 936-950, April 2025.
This study unveiled the mechanism wherein IGF2BP3 was overexpressed in human LUAD tissues, promoted cell migration and invasion, EMT, lymphangiogenesis, and lymph node metastasis by binding the m6A site of the 3′UTR region of SRC and maintaining its stability to activate STAT3 signaling pathway, and promote VEGFC expression in LUAD.
Jiapei Ding, Xuequan Wang, Haihua Yang, Lele Zhang, Yongquan Ying, Wenhu Pi, Guozhong Deng, Yaqun Zhu   +7 more
wiley   +1 more source

N6-Methyladenosine–binding proteins suppress HIV-1 infectivity and viral production

, 2018
Wuxun Lu, Nagaraja Tirumuru, Corine St. Gelais, Pratibha C. Koneru, Chang Liu, Mamuka Kvaratskhelia, Chuan He, Li Wu   +7 more
openalex   +1 more source

Arabidopsis N6-methyladenosine reader CPSF30-L recognizes FUE signals to control polyadenylation site choice in liquid-like nuclear bodies [PDF]

, 2021
Peizhe Song, Jun‐Bo Yang, Chunling Wang, Qiang Lu, Linqing Shi, Subiding Tayier, Guifang Jia   +6 more
openalex   +1 more source

Transcriptome‐wide alternative mRNA splicing analysis reveals post‐transcriptional regulation of neuronal differentiation

The FEBS Journal, Volume 292, Issue 8, Page 2051-2070, April 2025.
During differentiation of SH‐SY5Y neuroblastoma cells to mature neuron‐like cells, transcriptome‐wide alternative splicing events occur in multiple local splice variant programs. These events are driven by RNA‐binding proteins (RBPs). Here, we utilize sequencing analysis to explore these events as well as identifying their potential RBP regulators via ...
Yuan Zhou, Sherif Rashad, Kuniyasu Niizuma   +2 more
wiley   +1 more source

N6-Methyladenosine Role in Cancer: Learning from AML

, 2018
Zaira Ianniello, Alessandro Fatica
openalex   +1 more source

Emerging roles of N6-methyladenosine (m6A) modification in breast cancer [PDF]

, 2020
Yanyan Wang, Yujie Zhang, Yushen Du, Meiqi Zhou, Yue Hu, Suzhan Zhang   +5 more
openalex   +1 more source

N6-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner [PDF]

, 2021
Leilei Zhou, Renkun Tang, Xiaojing Li, Shiping Tian, Bingbing Li, Guozheng Qin   +5 more
openalex   +1 more source

ATP13A2 as a prognostic biomarker and its correlation with immune infiltration in cervical cancer: A retrospective study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
Abstract While the oncogene ATP13A2 is reportedly involved in colorectal cancer, its role in cervical cancer (CC) has yet to be fully characterized. In this study, we investigated ATP13A2 as a potential prognostic biomarker of CC. To this end, we compared CC tissues with normal tissues to identify differentially expressed genes, identifying ATP13A2 as ...
Zhi Zhao, Yijie Peng, Yuanyuan Yang, Shuaiyu Li, Jiang Ling, Zhenyu Zhu, Chenfeng He   +6 more
wiley   +1 more source

RNA N6-methyladenosine modification is required for miR-98/MYCN axis-mediated inhibition of neuroblastoma progression [PDF]

, 2020
Junmei Cheng, Lingling Xu, Liqiang Deng, Lan Xue, Qingmei Meng, Furong Wei, Jinghua Wang   +6 more
openalex   +1 more source

Comprehensive Analysis of GPSM2: From Pan‐Cancer Analysis to Experimental Validation

Journal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
ABSTRACT G‐protein signalling modulator 2 (GPSM2) plays an important role in maintaining cell polarisation and regulating the cell cycle; however, a systematic and comprehensive analysis of GPSM2 in cancer is still lacking. Using extensive multi‐omics data, we explored the pan‐cancer expression levels of GPSM2 from multiple perspectives and its ...
Chunjiao Yang, Yuzhe Zhang, Lirong Yan, Aoran Liu, Fang Li, Yanke Li, Ye Zhang   +6 more
wiley   +1 more source