Results 141 to 150 of about 41,595,656 (345)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI) Dong‐Woo Shin, Tingting Chen, James A. Letts +2 morewiley +1 more sourceMeta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Nature Genetics, 2010 I. Heid, A. Jackson, J. Randall, T. Winkler, L. Qi, V. Steinthorsdottir, G. Thorleifsson, M. Zillikens, Elizabeth K. Speliotes, R. Mägi, T. Workalemahu, Charles White, N. Bouatia-Naji, T. Harris, S. Berndt, E. Ingelsson, C. Willer, M. Weedon, J. Luan, S. Vedantam, T. Esko, T. Kilpeläinen, Z. Kutalik, Shengxu Li, K. Monda, A. Dixon, C. Holmes, L. Kaplan, L. Liang, J. Min, M. Moffatt, C. Molony, G. Nicholson, E. Schadt, K. Zondervan, M. Feitosa, T. Ferreira, H. L. Allen, R. Weyant, E. Wheeler, A. Wood, K. Estrada, M. Goddard, G. Lettre, M. Mangino, D. Nyholt, S. Purcell, A. Smith, P. Visscher, Jian Yang, S. Mccarroll, J. Nemesh, B. Voight, D. Absher, N. Amin, T. Aspelund, L. Coin, N. Glazer, C. Hayward, N. Heard-Costa, J. Hottenga, Å. Johansson, T. Johnson, M. Kaakinen, K. Kapur, Shamika Ketkar, J. Knowles, P. Kraft, A. Kraja, C. Lamina, M. Leitzmann, B. McKnight, A. Morris, K. Ong, J. Perry, M. Peters, O. Polašek, I. Prokopenko, N. W. Rayner, S. Ripatti, F. Rivadeneira, N. Robertson, S. Sanna, U. Sovio, I. Surakka, A. Teumer, S. V. Wingerden, V. Vitart, J. Zhao, Christine Cavalcanti-Proença, P. Chines, E. Fisher, Jennifer R Kulzer, C. Lecoeur, Narisu Narisu, C. Sandholt, L. Scott, K. Silander, K. Stark, Mari-Liis Tammesoo, T. Teslovich, N. Timpson, R. Watanabe, Ryan Welch, D. Chasman, M. Cooper, J. Jansson, J. Kettunen, R. Lawrence, Niina Pellikka, M. Perola, L. Vandenput, Helene Alavere, P. Almgren, L. Atwood, A. Bennett, R. Biffar, L. Bonnycastle, S. Bornstein, T. Buchanan, H. Campbell, I. Day, Mariano Dei, M. Dörr, P. Elliott, M. Erdos, J. Eriksson, N. Freimer, Mao Fu, Stefan Gaget, E. D. Geus, A. Gjesing, H. Grallert, J. Grässler, C. Groves, C. Guiducci, A. Hartikainen, N. Hassanali, A. Havulinna, K. Herzig, A. Hicks, J. Hui, W. Igl, P. Jousilahti, A. Jula, E. Kajantie, L. Kinnunen, I. Kolčić, S. Koskinen, P. Kovacs, H. Kroemer, V. Krželj, J. Kuusisto, K. Kvaløy, J. Laitinen, O. Lantieri, G. Lathrop, M. Lokki, R. Luben, B. Ludwig, W. McArdle, Anne McCarthy, M. Morken, M. Nelis, M. Neville, G. Paré, A. Parker, J. Peden, I. Pichler, K. Pietiläinen, Carl G. P. Platou, A. Pouta, M. Ridderstråle, N. Samani, J. Saramies, J. Sinisalo, J. Smit, R. Strawbridge, H. Stringham, A. Swift, M. Teder-Laving, Brian Thomson, G. Usala, J. Meurs, G. V. Ommen, V. Vatin, C. Volpato, H. Wallaschofski, G. Walters, E. Widén, S. Wild, G. Willemsen, D. Witte, L. Zgaga, P. Zitting, J. Beilby, A. James, M. Kähönen, T. Lehtimäki, M. Nieminen, C. Ohlsson, L. Palmer, O. Raitakari, P. Ridker, M. Stumvoll, A. Tönjes, J. Viikari, B. Balkau, Y. Ben-Shlomo, R. Bergman, H. Boeing, G. Smith, S. Ebrahim, P. Froguel, T. Hansen, C. Hengstenberg, K. Hveem, B. Isomaa, T. Jørgensen, F. Karpe, K. Khaw, M. Laakso, D. Lawlor, M. Marre, T. Meitinger, A. Metspalu, K. Midthjell, O. Pedersen, V. Salomaa, P. Schwarz, T. Tuomi, J. Tuomilehto, T. Valle, N. Wareham, A. Arnold, J. Beckmann, S. Bergmann, E. Boerwinkle, D. Boomsma, M. Caulfield, F. Collins, G. Eiriksdottir, V. Gudnason, U. Gyllensten, A. Hamsten, A. Hattersley, A. Hofman, F. Hu, T. Illig, C. Iribarren, M. Jarvelin, W. Kao, J. Kaprio, L. Launer, P. Munroe, B. Oostra, B. Penninx, P. Pramstaller, B. Psaty, T. Quertermous, A. Rissanen, I. Rudan, A. Shuldiner, N. Soranzo, T. Spector, A. Syvanen, M. Uda, A. Uitterlinden, H. Völzke, P. Vollenweider, James F. Wilson, J. Witteman, A. Wright, G. Abecasis, M. Boehnke, I. Borecki, P. Deloukas, T. Frayling, L. Groop, T. Haritunians, D. Hunter, R. Kaplan, K. North, J. O’Connell, L. Peltonen, D. Schlessinger, D. Strachan, J. Hirschhorn, T. Assimes, H. Wichmann, U. Thorsteinsdóttir, C. Duijn, K. Stefánsson, L. Cupples, R. Loos, I. Barroso, M. McCarthy, C. Fox, K. Mohlke, C. Lindgren +299 moresemanticscholar +1 more sourceEnteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourceThe newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...Dylan Casey, Zeqian Gao, Joan Boyeswiley +1 more sourceInterleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.
Gastroenterology, 2005 F. Heller, P. Florian, C. Bojarski, J. Richter, M. Christ, Bernd Hillenbrand, J. Mankertz, A. Gitter, N. Bürgel, M. Fromm, M. Zeitz, I. Fuss, W. Strober, J. Schulzke +13 moresemanticscholar +1 more source
