Results 151 to 160 of about 41,595,656 (345)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Cowl - v.30 - n.13 - Mar 07, 1968 [PDF]
, 1968 The Cowl - student newspaper of Providence College. Volume 30, Number 13 - March 07, 1968.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Enhancing relative humidity modelling using L2 regularization updates
Scientific ReportsThis study explores L2 regularization to mitigate overfitting in artificial neural networks (ANNs), focusing on the regularization coefficient, Lambda, and its effect on data distribution and multi-layer perceptron (MLP) performance.
Abdellah Ben Yahia +3 more
doaj +1 more source
Encontros Bibli: revista eletrônica de biblioteconomia e ciência da informação, 2007 Comissão editorial do n. 13, 2002 Editora Miriam Vieira da Cunha – Professora no Departamento de Ciência da Informação da Universidade Federal de Santa Catarina – Florianópolis, SC, Brasil. Eliany Alvarenga de Araújo – Professora na Universidade Federal da Paraíba – João Pessoa, PB, Brasil.
openaire +3 more sources
The Cowl - v.29 - n.13 - Sep 29, 1976 [PDF]
, 1976 The Cowl - student newspaper of Providence College. Volume 29, Number 13 - September 29, 1976. 12 pages. Note: The volume number printed on the banner page of this issue (XXIX) duplicates the volume number for the 1966-67 academic ...
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Cowl - v.13 - n.17 - Mar 6, 1951 [PDF]
, 1951 The Cowl - student newspaper of Providence College. Volume 13, Number 17- Mar 6, 1951.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source