Results 121 to 130 of about 5,783,535 (228)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

A morphological and phylogenetic analysis of dematiaceous hyphomycete strains of <i>Distoseptispora</i> (<i>Distoseptisporaceae</i>, <i>Distoseptisporales</i>) and <i>Kirschsteiniothelia</i> (<i>Kirschsteiniotheliaceae</i>, <i>Pleosporales</i>) in southern China. [PDF]

MycoKeys
He Y, Wang X, Yan X, Liu W, Jiang Y, Ai C, Sheng J, Zhang X, Wang S.   +8 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The impact of telemedicine on the efficiency and accuracy of emergency department triage: a staff perspective. [PDF]

BMC Emerg Med
Qureshi MN, Aldukhayl H, Alnatheer A, Ahmad IN, Alshehry A.   +4 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Cognitive Rehabilitation Interventions in the Intensive Care Unit: A Systematic Integrative Review. [PDF]

Acta Anaesthesiol Scand
Lassen KC, Laerkner E, Jensen JF, Egerod I, Christensen J, Jørgensen K, Kjærgaard RS, Olausson S, Wøien H, Nielsen AH, Kjær MN, Bruun CRL, Gamst-Jensen H, Perner A, Collet MO.   +14 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

EPICRONI: Programa automatizado para el monitoreo y evaluación de la calidad de la atención médica de las enfermedades no transmisibles

Revista Cubana de Higiene y Epidemiología
RESUMEN EPICRONI, es un sistema útil para el procesamiento automatizado del monitoreo y evaluación de la calidad de la atención médica. Está diseñado como el complemento analítico de una metodología para evaluar la calidad de la atención médica que se ...
Diana Rodríguez Gabaldá, Milvia Ramírez Rodríguez, Orlando Landrove, Carmen Serrano Verdura, Manuel Santín Peña, Cristina Valdivia Omega   +5 more
doaj  

Liasse n°23 LEGUMINOSAE

, 1886
Herbier de Jean-Baptiste LAMARCK au Muséum National d'Histoire Naturelle de Paris, 167 ...
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source