Results 111 to 120 of about 21,434,952 (294)
The Cowl - v.47 - n.14 - Jan 23, 1985 [PDF]
The Cowl - student newspaper of Providence College. Vol 47 - No. 14 - January 23, 1985.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Credit Investments in Northern Italian States (17th–18th Centuries)
This article examines investment opportunities in northern Italian states in the 17th and 18th centuries, with a focus on the private credit market. The research is based on loan contracts drawn up by notaries and on fiscal and administrative documents ...
Lorenzini Marcella
doaj +1 more source
The Cowl - v.17 - n.15 - Mar 23, 1955 [PDF]
The Cowl - student newspaper of Providence College. Volume 17, Number 15 - Mar 23, 1955.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Cowl - v.79 - n.7 - Oct 23, 2014 [PDF]
The Cowl - student newspaper of Providence College. Vol 79 - No. 7 - October 23, 2014.
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Cowl - v.78 - n.23 - May 1, 2014 [PDF]
The Cowl - student newspaper of Providence College. Volume 78 - No. 23 - May 1, 2014.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

