Results 111 to 120 of about 22,183,063 (244)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Disposición UNRN-SIDTT N° 23/2009. Aceptar la solicitud de inclusión.
, 2009 Fil: Secretaría de Investigación, Creación Artística, Desarrollo y Transferencia de Tecnología (I). Universidad Nacional de Río Negro. Río Negro, ArgentinaDisposición UNRN-SIDTT N° 23/2009.
Secretaría de Investigación, Creación Artística, Desarrollo y Transferencia de Tecnología (I)
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2015 Atualizado até 07/04/2015.Disponível, também,os arquivos de outras edições.Disponível, também, em formato impresso e digital (PDF).Lei n. 12.965, de 23 de abril de 2014, que estabelece princípios, garantias, direitos e deveres para o uso da internet no ...
Brasil. [Lei n. 12.965, de 23 de abril de 2014]
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Ato n. 310/CSJT.GP.SG, de 23 de outubro de 2014
, 2014 Transforma e transfere funções comissionadas no âmbito do Conselho Superior da Justiça do Trabalho.RetificadoArt. 4º retificado pelo Ato n.
Conselho Superior da Justiça do Trabalho (Brasil) (CSJT)
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 1980 v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through the kind support of The Stony Brook Alumni ...
Stony Brook University Statesman
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