Results 131 to 140 of about 21,434,952 (294)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Cowl - v.23 - n.8 - Dec 07, 1960 [PDF]
, 1960 The Cowl - student newspaper of Providence College. Volume 23, Number 8 - December 7, 1960.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Environmental Research: ClimateWe examine sources of uncertainty in projections of Arctic amplification (AA) using the CMIP6 multi-model (MM) ensemble and single model initial-condition large ensembles of historical and future scenario simulations.
Stephanie Hay +2 more
doaj +1 more source
The Cowl - v.56 - n.11 - Jan 23, 1992 [PDF]
, 1992 The Cowl - student newspaper of Providence College. Volume 56, Number 11 - January 23, 1992.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Cowl - v.23 - n.7 - Nov 30, 1960 [PDF]
, 1960 The Cowl - student newspaper of Providence College. Volume 23, Number 7 - Novmeber 30, 1960.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Cowl - v.23 - n.10 - Feb 08, 1961 [PDF]
, 1961 The Cowl - student newspaper of Providence College. Volume 23, Number 10 - February 8, 1961.
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source