Results 211 to 220 of about 18,243,204 (281)

Confins n° 43 - 2019

, 2019
openaire   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Semina: Ciênc. Agrár. Londrina, v. 43, n. 4, 2022

Semina: Ciências Agrárias, 2022
doaj  

Editorial do volume 43, n.1 (2025)

Horizontes
Sônia Aparecida Siquelli, Fabiana Rodrigues de Sousa , Márcia Aparecida Amador Mascia , Renata Helena Pin Pucci , Karina Carrasqueira Lopes   +4 more
doaj   +1 more source

Health economic evaluation of health promotion and disease prevention in Germany: a scoping review. [PDF]

Health Econ Rev
Beer EJ, Kirschneck M, Coenen M, Visscher RMS.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Semina: Ciências Sociais e Humanas, v. 43, n. 2, jul./dez. 2022

Semina: Ciências Sociais e Humanas, 2023
Dircel Aparecida Kailer
doaj  

Sorafenib/piroxicam therapy with biomarker-defined survival benefit in canine muscle-invasive urothelial carcinoma. [PDF]

Sci Rep
Maeda S, Yokota S, Komori M, Goto-Koshino Y, Chambers JK, Uchida K, Yonezawa T, Momoi Y.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source