Results 191 to 200 of about 18,243,204 (281)

Patient and Public Involvement and Engagement in Pediatric Health Research: A Systematic Review. [PDF]

Health Expect
Stadler V, Mozun R, Strohm J, Consortium S, Caruso C, Posfay-Barbe KM, Hagmann C.   +6 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Ultra-rapid outpatient treatment of patients with severe aortic stenosis presenting with acute valve syndrome: evaluation of a novel pathway for urgent TAVI. [PDF]

Open Heart
Vibhishanan J, Winn K, Ferreira-Martins J, Sharma H, Hosin A, Konstanciak K, Matos Dias J, Gurreiro De Almeida J, Hundertmark C, Bulman S, Fullerton JN, Dawkins S, Franks R, Kharbanda RK, Newton JD, Banning AP, Cahill TJ.   +16 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Semina: Ciências Agrárias, Londrina, v. 43, n. 6, nov./dez. 2022

Semina: Ciências Agrárias, 2022
Semina agrarias
doaj  

Predicting neurological recovery after thoracolumbar spine trauma: The role of injury morphology and admission American Spinal Injury Association Impairment Scale grade. [PDF]

J Craniovertebr Junction Spine
Khursheed A, Ayoub I, Fayaz M, Reza A, Chhiber SS.   +4 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Locus coeruleus TDP-43 pathology in a community-based cohort: Clinical and pathological correlates. [PDF]

J Neuropathol Exp Neurol
Neltner AM, Shahidehpour RK, Hall ME, Ning X, Fister S, Kang H, Anderson S, Jicha GA, Lee TL, Abner EL, Fardo DW, Nelson PT.   +11 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

The UNC13A cryptic exon associates with cognitive impairment in Alzheimer's disease. [PDF]

Alzheimers Res Ther
Reeves MM, Aviles Carpintero S, Zanovello M, Jansen-West K, Yue M, Calliari A, Song Y, Dunmore J, Maroto Cidfuentes C, Ball S, Kachergus JM, Killeen HE, Rawlinson B, Engelberg-Cook E, DeTure M, Day GS, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Murray M, Thompson AE, Dickson DW, Fratta P, Petrucelli L, Josephs KA, Prudencio M.   +26 more
europepmc   +1 more source