Results 171 to 180 of about 14,888,422 (277)

Preventive exercise intervention for trismus in head and neck cancer - a randomized study : Preventive exercise intervention for trismus. [PDF]

Clin Oral Investig
Pauli N, Tuomi L, Lindell E, Larsson H, Finizia C.   +4 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

APOE-mediated sex differences in microvascular pathology and AD-associated proteinopathies in the medial temporal lobe. [PDF]

Alzheimers Dement
Bax F, Oltmer J, Auger CA, Bonkhoff A, Coughlan GT, Melloni A, Jaisa-Aad M, Augustinack J, Serrano-Pozo A, Frosch MP, Greenberg SM, Gomez-Isla T, Hyman BT, van Veluw SJ, Perosa V.   +14 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

N°43-1er semestre 2015

Histoire & sociétés rurales, 2015
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Semina: Ciências Agrárias, Londrina, v. 43, n. 6, nov./dez. 2022

Semina: Ciências Agrárias, 2022
Semina agrarias
doaj  

Severe maternal morbidity and re-hospitalisation in the first postpartum year within Canada, 2008-2020: a population-based retrospective cohort study. [PDF]

BMJ Public Health
Blackman A, Ukah UV, Platt RW, Shapiro GD, Lisonkova S, Malhamé I, Ray JG, El-Chaâr D, Auger N, Dayan N.   +9 more
europepmc   +1 more source

Bulletin de la SIEY, n° 43

Self XX-XXI, 2023
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source