Results 161 to 170 of about 18,243,204 (281)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Statesman V. 51, n. 43

, 2008
v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through a grant from the Stony Brook Alumni ...
Stony Brook University Statesman
core  

TMEM106B is a selective modulator of TDP-43 pathology in Alzheimer's disease. [PDF]

Alzheimers Dement
Reeves MM, Calliari A, Todd TW, Maroto Cidfuentes C, Jansen-West K, Yue M, Song Y, Dunmore J, Rawlinson B, Engelberg-Cook E, DeTure M, Day GS, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Cook CN, Murray ME, Dickson DW, Josephs KA, Petrucelli L, Prudencio M.   +21 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Statesman, V. 44, n. 43

, 2000
v. : ill.; 32 cm (original analog pub.)Archived web contentThe digital publication of the Stony Brook Statesman was made possible through a grant from the Stony Brook Alumni ...
Stony Brook University Statesman
core  

Real-life evaluation of BioFire® BCID2 and Vitek® REVEALTM for Gram-negative bloodstream infections in critical care. [PDF]

PLoS One
Benyahia M, Roger C, Boutet-Dubois A, Salipante F, Oudiane L, Curtil Dit Galin M, Nsiri R, Brochon L, Lavigne JP, Pantel A.   +9 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Assessment of the posterior pelvic ring during examination under anesthesia changes surgeons' classification and treatment decisions of anterior posterior compression pelvic ring injuries. [PDF]

Eur J Orthop Surg Traumatol
Therrien CC, Ten Duis K, Aprato A, Banierink H, Mezzadri UMR, Sagi HC, de Vries JPM, Reininga IHF, IJpma FFA, Society of European Pelvic and Acetabulum Surgeons.   +9 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

The Critical Care Pain Observation Tool for Families (CPOT-Fam). [PDF]

Can J Pain
Shahid A, Sept BG, Johnstone C, Owen VS, Moss SJ, Brundin-Mather R, Krewulak KD, Soo A, Parsons Leigh J, Gélinas C, Fiest KM, Stelfox HT.   +11 more
europepmc   +1 more source