Results 51 to 60 of about 3,497,773 (231)

Indebted Abbots: The Impact of Lordly Demand on the Late Medieval Rural Economy in Northeast Scotland

Jahrbuch für Wirtschaftsgeschichte
Scottish historiography often describes late medieval Scotland as experiencing socio-economic stagnation while at the same time witnessing a shift from feudal to post-feudal lordship. This paper reevaluates that interpretation through a case study of the
Weil Sebastian
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Investment and Saving Opportunities for Different Socio-Economic Groups in Medieval and Early Modern Europe

Jahrbuch für Wirtschaftsgeschichte
This special issue focuses on the financial behaviour of different participants in European medieval and early modern financial markets. It extends our knowledge of the financial strategies employed by households, merchants, charities, city governments ...
Nicolussi-Köhler Stephan, Conti Marco, Wandschneider Kirsten   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Politics, Investments and Public Spending in Bologna (End of 13th – First Half of 14th Century)

Jahrbuch für Wirtschaftsgeschichte
Not all major Italian cities of the late Middle Ages could rely on an established and organised system of public debt like Florence, Venice, Genoa, and others.
Conti Marco
doaj   +1 more source

KINERJA GURU BIMBINGAN DAN KONSELING SERTA PEMBINAANNYA

Enlighten, 2018
Penelitian ini dilakukan karena pelaksanaan layanan bimbingan dan konseling di sekolah tidak berjalan dengan baik terutama dalam pembinaan guru bimbingan dan konseling. Ada tiga tujuan dari penelitian ini.
Sisca Meidina Saputri, Prayitno Prayitno, Yahya Jaya   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Manorial Plunder: Serfdom and Material Culture in Fifteenth-Century England

Jahrbuch für Wirtschaftsgeschichte
Heriot was a due paid by manorial tenants to their lords when they died, traditionally in the form of their best beast. Unlike other customary dues associated with serfdom that gradually disappeared from manorial courts in the later 14th and 15th ...
Johnson Tom
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source