Results 71 to 80 of about 18,243,204 (281)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Whose was the Fifteenth-century Manor Court?

Jahrbuch für Wirtschaftsgeschichte
As part of a wider literature challenging the notion that many lords engaged in extensive surplus extraction, a recent study focused on inland Flanders has argued that we need to decouple seigneuries, the institutions which structured lordship on the ...
Gibbs Spike
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Resolución CSDEyVE N° 43/2019. Establecer la obligatoriedad del examen Certificado de Español, Lengua y Uso -CELU-

, 2019
Fil: Consejo Superior de Docencia, Extensión y Vida Estudiantil (D). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CSDEyVE N° 43/2019.
Consejo Superior de Docencia, Extensión y Vida Estudiantil (D)
core  

Lordship, Land Markets and Rural Economic Development in the Eastern Low Countries c. 1460 to 1570

Jahrbuch für Wirtschaftsgeschichte
Seigneurial lordship is often considered detrimental to economic development. Through exercising their claims to political power, lords are believed to have hindered the rise of pervasive and efficient factor and commodity markets, presenting ...
Klinkhamer Reinder
doaj   +1 more source

So What ? n°43

Observatoire du Brexit
À la une ce mois-ci, pour le premier éditorial de l’année, une actualité internationale chargée. Alors que l’on célébrera dans quelques mois les dix ans du vote de sortie de l’UE, on assiste à un rapprochement manifeste du Royaume-Uni avec ses voisins européens. Parallèlement, sa « relation spéciale » avec les États-Unis paraît s’étioler.
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Was Serfdom Good for the Economy?

Jahrbuch für Wirtschaftsgeschichte
Some recent theories have sought to rehabilitate serfdom, postulating that it could have been economically beneficial because lords used their institutional power to address pre-modern market failures.
Ogilvie Sheilagh
doaj   +1 more source

Editorial V. 43 N. 2 - A hora do adeus

Revista Contracampo
Editorial V.
Camilla Quesada Tavares
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source