Results 81 to 90 of about 14,888,422 (277)

KINERJA GURU BIMBINGAN DAN KONSELING SERTA PEMBINAANNYA

open access: yesEnlighten, 2018
Penelitian ini dilakukan karena pelaksanaan layanan bimbingan dan konseling di sekolah tidak berjalan dengan baik terutama dalam pembinaan guru bimbingan dan konseling. Ada tiga tujuan dari penelitian ini.
Sisca Meidina Saputri   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Manorial Plunder: Serfdom and Material Culture in Fifteenth-Century England

open access: yesJahrbuch für Wirtschaftsgeschichte
Heriot was a due paid by manorial tenants to their lords when they died, traditionally in the form of their best beast. Unlike other customary dues associated with serfdom that gradually disappeared from manorial courts in the later 14th and 15th ...
Johnson Tom
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Whose was the Fifteenth-century Manor Court?

open access: yesJahrbuch für Wirtschaftsgeschichte
As part of a wider literature challenging the notion that many lords engaged in extensive surplus extraction, a recent study focused on inland Flanders has argued that we need to decouple seigneuries, the institutions which structured lordship on the ...
Gibbs Spike
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Lordship, Land Markets and Rural Economic Development in the Eastern Low Countries c. 1460 to 1570

open access: yesJahrbuch für Wirtschaftsgeschichte
Seigneurial lordship is often considered detrimental to economic development. Through exercising their claims to political power, lords are believed to have hindered the rise of pervasive and efficient factor and commodity markets, presenting ...
Klinkhamer Reinder
doaj   +1 more source

Editorial V. 43 N. 2 - A hora do adeus

open access: yesRevista Contracampo
Editorial V.
Camilla Quesada Tavares
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Was Serfdom Good for the Economy?

open access: yesJahrbuch für Wirtschaftsgeschichte
Some recent theories have sought to rehabilitate serfdom, postulating that it could have been economically beneficial because lords used their institutional power to address pre-modern market failures.
Ogilvie Sheilagh
doaj   +1 more source

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