Results 61 to 70 of about 3,497,773 (231)
Whose was the Fifteenth-century Manor Court?
Jahrbuch für WirtschaftsgeschichteAs part of a wider literature challenging the notion that many lords engaged in extensive surplus extraction, a recent study focused on inland Flanders has argued that we need to decouple seigneuries, the institutions which structured lordship on the ...
Gibbs Spike
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Lordship, Land Markets and Rural Economic Development in the Eastern Low Countries c. 1460 to 1570
Jahrbuch für WirtschaftsgeschichteSeigneurial lordship is often considered detrimental to economic development. Through exercising their claims to political power, lords are believed to have hindered the rise of pervasive and efficient factor and commodity markets, presenting ...
Klinkhamer Reinder
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Editorial V. 43 N. 2 - A hora do adeus
Revista ContracampoEditorial V.
Camilla Quesada Tavares
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Was Serfdom Good for the Economy?
Jahrbuch für WirtschaftsgeschichteSome recent theories have sought to rehabilitate serfdom, postulating that it could have been economically beneficial because lords used their institutional power to address pre-modern market failures.
Ogilvie Sheilagh
doaj +1 more source
Observatoire du BrexitÀ la une ce mois-ci, pour le premier éditorial de l’année, une actualité internationale chargée. Alors que l’on célébrera dans quelques mois les dix ans du vote de sortie de l’UE, on assiste à un rapprochement manifeste du Royaume-Uni avec ses voisins européens. Parallèlement, sa « relation spéciale » avec les États-Unis paraît s’étioler.
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Reproductive health indicators and fetal medicine – many things will change
Scandinavian Journal of Work, Environment & Health, 2016 Reproductive epidemiologists study disease outcomes over three time periods: (i) from conception, or before, to birth, (ii) from birth to death and (iii) from death and into the next generations.
Jørn Olsen, Lars Henning Pedersen
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