Results 131 to 140 of about 1,792,273 (291)

Boletín Diario Oceanográfico vol.5 N°83, 2018 [PDF]

open access: yes, 2018
Reporta información diaria relacionada a las temperaturas y anomalías del nivel de superficie del ambiente marino y lacustre del Perú, en base a registros in situ y de percepción remota, con el propósito de monitorear las condiciones térmicas asociadas a
Instituto del Mar del Perú. Dirección General de Investigaciones en Oceanografía y Cambio Climático. Laboratorio de Hidrofísica Marina
core  

Exploiting the Biorefinery Potential of Spent Mushroom Substrate: The Time to Do It Is Now

open access: yesMolecules
Spent mushroom substrate (SMS), the residual material left after mushroom cultivation, represents an abundant yet underutilized bioresource. With global mushroom production generating millions of tons of SMS annually, its disposal constitutes a missed ...
Carlos Martín   +2 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Boletín Diario Oceanográfico vol.1 N°83, 2014 [PDF]

open access: yes, 2014
Reporta información diaria relacionada a las temperaturas y anomalías del nivel de superficie del ambiente marino y lacustre del Perú, en base a registros in situ y de percepción remota, con el propósito de monitorear las condiciones térmicas asociadas a
Instituto del Mar del Perú. Dirección General de Investigaciones Oceanográficas y Cambio Climático
core  

A-Differentiability over Associative Algebras

open access: yesMathematics
The unital associative algebra structure A on Rn allows for defining elementary functions and functions defined by convergent power series. For these, the usual derivative has a simple form even for higher-order derivatives, which allows us to have the A-
Julio Cesar Avila   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Verlustliste Nr. 83. (Nr. 83. /1914) [PDF]

open access: yes, 1914
VERLUSTLISTE NR. 83. Verlustliste (-) Verlustliste Nr. 83. (Nr. 83. /1914) ([1]) Belehrung. (2) Offiziere. (4) A, B, C, D, F, G, H, I, J (4) K (4) L, M, N, P, R, S, T, U, V, W ...

core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Études marxistes n° 83 – juillet / septembre 2008 : L’Iran en ligne de mire, (Bruxelles, Belgique) [PDF]

open access: yes, 2008
Rogalski Michel. Études marxistes n° 83 – juillet / septembre 2008 : L’Iran en ligne de mire, (Bruxelles, Belgique). In: Recherches Internationales, n°83, 2008. L’Amérique que nous lègue G. W. bush.
Rogalski, Michel
core  

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