Results 111 to 120 of about 1,573,473 (242)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Boletín Diario Oceanográfico vol.3 N°93, 2016 [PDF]
, 2016 Reporta información diaria relacionada a las temperaturas y anomalías del nivel de superficie del ambiente marino y lacustre del Perú, en base a registros in situ y de percepción remota, con el propósito de monitorear las condiciones térmicas asociadas a
Instituto del Mar del Perú. Dirección General de Investigaciones Oceanográficas y Cambio Climático
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Parecer n. 93 de 5 de março de 2018 [PDF]
, 2018 Minuta de edital do pregão eletrônico n. 41/2018 - tipo menor preço global. Inspeção, manutenção e substituição. Mangueiras de incêndio. Fundamentação com base nas Leis n. 8.666/93 e n. 10.520/2002, nos Decretos n.
Almeida, Wélida Cristina Silveira de +1 more
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CNKI(
Huli yanjiu, 2019 ObjectiveTo systematically evaluate the effect of pinch training on urinary function in patients with a short-term indwelling catheter.MethodsThe randomized controlled trials(RCTs) of pinch training and continuous open drainage that performed in patients
汪涓 +4 more
doaj
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Boletín Diario Oceanográfico vol.5 N°93, 2018 [PDF]
, 2018 Reporta información diaria relacionada a las temperaturas y anomalías del nivel de superficie del ambiente marino y lacustre del Perú, en base a registros in situ y de percepción remota, con el propósito de monitorear las condiciones térmicas asociadas a
Instituto del Mar del Perú. Dirección General de Investigaciones en Oceanografía y Cambio Climático. Laboratorio de Hidrofísica Marina
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Boletín Diario Oceanográfico vol.2 N°93, 2015 [PDF]
, 2015 Reporta información diaria relacionada a las temperaturas y anomalías del nivel de superficie del ambiente marino y lacustre del Perú, en base a registros in situ y de percepción remota, con el propósito de monitorear las condiciones térmicas asociadas a
Instituto del Mar del Perú. Dirección General de Investigaciones Oceanográficas y Cambio Climático
core