Results 101 to 110 of about 1,573,473 (242)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Jahrbuch für WirtschaftsgeschichteThis article uses case studies from eastern Switzerland, southern Germany and Austria to analyse economic relationships between feudal lords and peasants in the late Middle Ages. The focus is on agriculture.
Sonderegger Stefan
doaj +1 more source
Object-Based Greenhouse Classification from GeoEye-1 and WorldView-2 Stereo Imagery
Remote Sensing, 2014 Remote sensing technologies have been commonly used to perform greenhouse detection and mapping. In this research, stereo pairs acquired by very high-resolution optical satellites GeoEye-1 (GE1) and WorldView-2 (WV2) have been utilized to carry out the ...
Manuel A. Aguilar +3 more
doaj +1 more source
Lordship, Land Markets and Rural Economic Development in the Eastern Low Countries c. 1460 to 1570
Jahrbuch für WirtschaftsgeschichteSeigneurial lordship is often considered detrimental to economic development. Through exercising their claims to political power, lords are believed to have hindered the rise of pervasive and efficient factor and commodity markets, presenting ...
Klinkhamer Reinder
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Parecer n. 93 de 1 de março de 2019 [PDF]
, 2019 Minuta do pregão eletrônico n. 26/2019. Tipo menor preço global. Contratação de seguro total para veículos de representação. Ampla participação de empresas. Fundamentação com base nas Leis n. 10.520/2002 e n. 8.666/93. Lei Complementar n.
Brasil. Superior Tribunal de Justiça (STJ). Assessoria Jurídica +1 more
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